Patient P-01843

Synthetic patientNBL-101 · Day 107 · 55–64 · M · baseline S14Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Improving

GI state

Unstable

Inflammatory state

Unstable

Nutritional resilience

Unstable

Discontinuation risk

96%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S14
Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 49 SC-12 recommended — Supportive Compound SC-12
Day 50 Patient accepted — Started SC-12 in the companion
Day 56 No meaningful change — Supportive Compound SC-12

What changed?

Trajectory began diverging from predicted response on Day 48.

Primary contributors, last 14 days

Toxicity-12
Inflammatory activity-6
GI instability+4
Nutritional resilience+2

What helped?

Supportive Compound SC-12Day 49
Result: no meaningful change

LIFE OS recommendation

GI Support Protocol GI-04

92%

probability of meaningful tolerance improvement

284 similar trajectories
83% showed improvement
median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

69.4/100

improving · -3.7 vs previous 14 d

Toxicity

Blood

41.3/100

improving · -2.9 vs previous 14 d

Sleep quality

Wearable

38/100

improving · +7.8 vs previous 14 d

Energy level

Daily log

2.7/10

improving · +0.3 vs previous 14 d

Stress level

Daily log

6.9/10

stable · -0.2 vs previous 14 d

Steps

Wearable

4,018

improving · +278 vs previous 14 d

Adherence

Companion

46.8 %

improving · +2.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 25 from the failing basin, 71 from restoration.

Would help

GI-04 GI Support Protocol
73% improved among 124 similar · onset 8 d · confidence 97%
ME-01 Monitoring Escalation
100% improved among 77 similar · onset 3 d · confidence 78%
NP-02 Dietary Support Protocol
63% improved among 64 similar · onset 10 d · confidence 78%

Would not help

SC-12 Supportive Compound
already tried, no meaningful change
Keep fat low
GI +6.4 next day on high-intake days · n 22
Keep fibre low
GI +3.3 next day on high-intake days · n 20

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+6.4detractor · 95%
Insoluble fibre
+3.3detractor · 79%
Spicy / capsaicin
-1.4no signal · 27%
Histamine load
-0.7no signal · 18%
Alcohol
+0.4no signal · 15%
Simple carbohydrates
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 69 and rising
Inflammatory signalling ↓25
- BloodInflammatory load index 58
Drug metabolism and exposure ↑20
- BloodToxicity index 41

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.1 · butyrate capacity 44/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 40 ms
Sleep: 7.1 h
Steps: 4,751
Resting HR: 69 bpm

Daily log: GI score 69, nutritional resilience 38, adherence 47.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01689	19%	S13	BR-03	no change	50
P-01350	18%	S19	BR-03	no change	34
P-01708	30%	S07	CR-01	improved	59
P-01371	25%	S06	CR-01	improved	63
P-01388	25%	S17	CR-01	improved	59
P-01835	25%	S17	CR-01	improved	56
P-01877	25%	S01	CR-01	improved	67
P-01696	24%	S20	CR-01	improved	59
P-01442	22%	S13	CR-01	improved	61
P-01430	19%	S05	CR-01	improved	54
P-01767	19%	S14	DT-01	no change	63
P-01342	18%	S11	DT-01	improved	48