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Patient P-01843

Synthetic patientNBL-101 · Day 107 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S14
  2. Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 49 SC-12 recommended — Supportive Compound SC-12
  4. Day 50 Patient accepted — Started SC-12 in the companion
  5. Day 56 No meaningful change — Supportive Compound SC-12

What changed?

Trajectory began diverging from predicted response on Day 48.

Primary contributors, last 14 days
  • Toxicity-12
  • Inflammatory activity-6
  • GI instability+4
  • Nutritional resilience+2

What helped?

  • Supportive Compound SC-12Day 49
    Result: no meaningful change
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 83% showed improvement
  • median effect visible after 8 days
View similar patientsSimulateAdd to intervention cohortAll evidence

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
69.4/100
improving · -3.7 vs previous 14 d
Toxicity
Blood
41.3/100
improving · -2.9 vs previous 14 d
Sleep quality
Wearable
38/100
improving · +7.8 vs previous 14 d
Energy level
Daily log
2.7/10
improving · +0.3 vs previous 14 d
Stress level
Daily log
6.9/10
stable · -0.2 vs previous 14 d
Steps
Wearable
4,018
improving · +278 vs previous 14 d
Adherence
Companion
46.8 %
improving · +2.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 25 from the failing basin, 71 from restoration.

Would help
  • GI-04 GI Support Protocol
    73% improved among 124 similar · onset 8 d · confidence 97%
  • ME-01 Monitoring Escalation
    100% improved among 77 similar · onset 3 d · confidence 78%
  • NP-02 Dietary Support Protocol
    63% improved among 64 similar · onset 10 d · confidence 78%
Would not help
  • SC-12 Supportive Compound
    already tried, no meaningful change
  • Keep fat low
    GI +6.4 next day on high-intake days · n 22
  • Keep fibre low
    GI +3.3 next day on high-intake days · n 20
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +6.4detractor · 95%
  • Insoluble fibre
    +3.3detractor · 79%
  • Spicy / capsaicin
    -1.4no signal · 27%
  • Histamine load
    -0.7no signal · 18%
  • Alcohol
    +0.4no signal · 15%
  • Simple carbohydrates
    +0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production ↓80
    • MicrobiomeButyrate capacity 44/100
    • MicrobiomeF. prausnitzii depleted
    • Daily logFibre intake low in recent food logs
  • Mucosal barrier integrity ↓50
    • MicrobiomeAkkermansia low → thinner mucus layer
    • Daily logGI symptom score 69 and rising
  • Inflammatory signalling ↓25
    • BloodInflammatory load index 58
  • Drug metabolism and exposure ↑20
    • BloodToxicity index 41
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Normal metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 44/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
40 ms
Sleep
7.1 h
Steps
4,751
Resting HR
69 bpm
Daily log: GI score 69, nutritional resilience 38, adherence 47.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0181342%S01NP-02no change40
P-0132739%S01GI-04improved56
P-0168831%S01GI-04improved40
P-0131028%S01——57
P-0187725%S01CR-01improved67
P-0182119%S01——58
P-0182319%S01——57
P-0184619%S01——37
P-0145233%S02GI-04improved46
P-0163532%S02GI-04improved49
P-0145926%S02——51
P-0149819%S02——56