Patient P-01871

Synthetic patientNBL-101 · Day 110 · 35–44 · M · baseline S16Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

25%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S16
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 HY-01 recommended — Hydration Protocol HY-01
Day 15 Patient accepted — Started HY-01 in the companion
Day 19 No meaningful change — Hydration Protocol HY-01

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

GI instability+8
Inflammatory activity+5
Nutritional resilience-3

What helped?

Hydration Protocol HY-01Day 14
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

25/100

worsening · +2.0 vs previous 14 d

Toxicity

Blood

16.2/100

worsening · +5.2 vs previous 14 d

Sleep quality

Wearable

34.1/100

worsening · -5.1 vs previous 14 d

Energy level

Daily log

5/10

worsening · -0.4 vs previous 14 d

Stress level

Daily log

4.5/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

3,832

stable · -112 vs previous 14 d

Adherence

Companion

93.4 %

stable · -1.0 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 66 from the failing basin, 23 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

HY-01 Hydration Protocol
already tried, no meaningful change
Keep fat low
GI +4.2 next day on high-intake days · n 22
Keep simple carbs low
GI +3.8 next day on high-intake days · n 18
Keep alcohol low
GI +3.5 next day on high-intake days · n 14

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+4.2detractor · 95%
Simple carbohydrates
+3.8detractor · 95%
Alcohol
+3.5detractor · 95%
Insoluble fibre
+1.4no signal · 35%
Spicy / capsaicin
+1.2no signal · 31%
Histamine load
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 32 ms, trending down
Autonomic recovery ↓45
- WearableResting HR 79 bpm
- Wearable3,832 steps/day
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 39/100
Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 1.9 · butyrate capacity 39/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 34 ms
Sleep: 7.4 h
Steps: 4,038
Resting HR: 74 bpm

Daily log: GI score 25, nutritional resilience 65, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01593	52%	S10	HY-01	improved	56
P-01342	51%	S11	DT-01	improved	48
P-01346	51%	S12	DT-01	improved	52
P-01585	50%	S13	—	—	49
P-01701	50%	S11	—	—	55
P-01787	50%	S19	—	—	51
P-01519	49%	S06	—	—	48
P-01823	49%	S01	—	—	57
P-01633	47%	S16	GI-04	no change	55
P-01884	47%	S19	GI-04	no change	54
P-01381	46%	S12	—	—	68
P-01818	46%	S15	—	—	46