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Patient P-03012

Synthetic patientONX-7 · Day 147 · 65–74 · F · baseline S11Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
37%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S11
  2. Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days
  • GI instability+12
  • Inflammatory activity+7
  • Treatment adherence-6
  • Nutritional resilience-5
  • Toxicity+5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    4.6/10
    worsening · -0.3 vs previous 14 d
    Stress level
    Daily log
    3.4/10
    worsening · +0.4 vs previous 14 d
    Pessimism score
    Daily log
    5.5/10
    worsening · +0.4 vs previous 14 d
    Sleep quality
    Wearable
    21.4/100
    worsening · -8.5 vs previous 14 d
    Libido
    Daily log
    5.3/10
    worsening · -0.4 vs previous 14 d
    HRV
    Wearable
    60.6 ms
    worsening · -3.4 vs previous 14 d
    Toxicity
    Blood
    16.6/100
    improving · -1.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 53 from the failing basin, 66 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -5.9 next day on high-intake days · n 25
    Would not help
    • AD-05 Adherence Support
      only 31% improved among 13 similar
    • Keep lactose low
      GI +4.4 next day on high-intake days · n 20
    • Keep caffeine low
      GI +4.1 next day on high-intake days · n 16
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.9supporter · 95%
    • Lactose
      +4.4detractor · 95%
    • Caffeine
      +4.1detractor · 95%
    • Alcohol
      +0.7no signal · 16%
    • Dietary fat load
      +0.1no signal · 15%
    • Histamine load
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery ↓45
      • WearableResting HR 73 bpm
      • WearableShort sleep window
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling ↑20
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓10
      • WearableSleep 4.9 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 45/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    64 ms
    Sleep
    5.6 h
    Steps
    6,255
    Resting HR
    72 bpm
    Daily log: GI score 30, nutritional resilience 62, adherence 83.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0323541%S13GI-04improved29
    P-0330740%S03ME-01improved17
    P-0342635%S18BR-03improved27
    P-0301333%S07GI-04improved30
    P-0337332%S17BR-03improved34
    P-0327730%S14BR-03improved41
    P-0338030%S16AD-05improved34
    P-0342429%S12AD-05improved41
    P-0311427%S11DT-01improved48
    P-0320427%S16AD-05improved48
    P-0321527%S16HY-01improved44
    P-0323327%S19DT-01improved47