Patient P-03013

Synthetic patientONX-7 · Day 139 · 25–34 · M · baseline S07Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S07
Day 23 GI-04 recommended — GI Support Protocol GI-04
Day 24 Patient accepted — Started GI-04 in the companion
Day 32 GI symptom burden −18% vs expected — GI Support Protocol GI-04
Day 36 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 38 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 36.

Primary contributors, last 14 days

Nutritional resilience+3
Treatment adherence-3

What helped?

GI Support Protocol GI-04Day 23
Result: symptom burden −18%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.7/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3.4/10

improving · -0.4 vs previous 14 d

Pessimism score

Daily log

4.7/10

improving · -0.4 vs previous 14 d

Sleep quality

Wearable

57/100

improving · +2.2 vs previous 14 d

Libido

Daily log

5.3/10

stable · -0.1 vs previous 14 d

HRV

Wearable

37.7 ms

stable · -0.6 vs previous 14 d

Toxicity

Blood

14.8/100

worsening · +3.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 82 from the failing basin, 50 from restoration.

Good elements to keep

GI Support Protocol GI-04
intervention · steering +19.8
Protein (supports)
perturbation · steering +8.1
Butyrate producers intact
hidden · steering +7.5
Histamine load (supports)
perturbation · steering +3.8
Protein
supporter · GI -4.7 next day
Histamine load
supporter · GI -2.4 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Bacteroides fragilis elevated
hidden · steering -7.4
Lactose
perturbation · steering -7.3
Caffeine
perturbation · steering -5.2
Lactose
detractor · GI +4.1 next day
Caffeine
detractor · GI +3.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.7supporter · 95%
Lactose
+4.1detractor · 95%
Caffeine
+3.4detractor · 94%
Histamine load
-2.4supporter · 65%
Alcohol
+1.4no signal · 36%
Dietary fat load
-0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 38 ms, trending down

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 3.1 · butyrate capacity 51/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 38 ms
Sleep: 7.2 h
Steps: 3,935
Resting HR: 68 bpm

Daily log: GI score 7, nutritional resilience 74, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03426	43%	S18	BR-03	improved	27
P-03235	39%	S13	GI-04	improved	29
P-03373	36%	S17	BR-03	improved	34
P-03307	33%	S03	ME-01	improved	17
P-03380	33%	S16	AD-05	improved	34
P-03233	31%	S19	DT-01	improved	47
P-03277	30%	S14	BR-03	improved	41
P-03424	30%	S12	AD-05	improved	41
P-03215	29%	S16	HY-01	improved	44
P-03114	27%	S11	DT-01	improved	48
P-03143	27%	S11	DT-01	improved	49
P-03204	27%	S16	AD-05	improved	48