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Patient P-03023

Synthetic patientONX-7 · Day 149 · 65–74 · F · baseline S16Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
19%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S16
  2. Day 58 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 58.

Primary contributors, last 14 days
  • Treatment adherence-6
  • GI instability-3
  • Nutritional resilience-2
  • Toxicity+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.1/10
    stable · -0.1 vs previous 14 d
    Stress level
    Daily log
    3.6/10
    stable · +0.1 vs previous 14 d
    Pessimism score
    Daily log
    2.5/10
    worsening · +0.2 vs previous 14 d
    Sleep quality
    Wearable
    29.7/100
    stable · -0.8 vs previous 14 d
    Libido
    Daily log
    4.8/10
    stable · -0.2 vs previous 14 d
    HRV
    Wearable
    47.4 ms
    stable · +1.6 vs previous 14 d
    Toxicity
    Blood
    27.1/100
    worsening · +3.5 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 80 from the failing basin, 8 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +12.3
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein
      supporter · GI -7.1 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Lactose
      perturbation · steering -11.7
    • Alcohol
      perturbation · steering -9.7
    • Caffeine
      perturbation · steering -7.8
    • Lactose
      detractor · GI +6 next day
    • Alcohol
      detractor · GI +5 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -7.1supporter · 95%
    • Lactose
      +6detractor · 95%
    • Alcohol
      +5detractor · 95%
    • Caffeine
      +4.7detractor · 95%
    • Histamine load
      -0.9no signal · 15%
    • Dietary fat load
      -0.4no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑75
      • DNACYP2D6 poor metabolizer → higher exposure
      • DNADPYD *2A → slower clearance
    • Inflammatory signalling ↑45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.7 h, below personal baseline
    • Autonomic recovery ↑20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.9 · butyrate capacity 64/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    53 ms
    Sleep
    6.3 h
    Steps
    8,933
    Resting HR
    61 bpm
    Daily log: GI score 18, nutritional resilience 60, adherence 84.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0325243%S13SC-12improved68
    P-0347342%S07DT-01improved70
    P-0305741%S14NP-02improved64
    P-0344941%S14DT-01improved79
    P-0317840%S11GI-04improved54
    P-0320837%S02BR-03improved57
    P-0317936%S05GI-04improved52
    P-0318836%S13HY-01improved79
    P-0337436%S19ME-01improved55
    P-0314435%S16HY-01improved52
    P-0332835%S15GI-04improved59
    P-0316534%S06NP-02improved79