Patient P-03034

Synthetic patientONX-7 · Day 149 · 55–64 · M · baseline S14Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

24%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S14
Day 56 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 90 AD-05 recommended — Adherence Support AD-05
Day 91 Patient accepted — Started AD-05 in the companion
Day 96 No meaningful change — Adherence Support AD-05

What changed?

Trajectory began diverging from predicted response on Day 56.

Primary contributors, last 14 days

GI instability-15
Nutritional resilience+8
Inflammatory activity+2
Treatment adherence+2

What helped?

Adherence Support AD-05Day 90
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

5.1/10

improving · +0.8 vs previous 14 d

Stress level

Daily log

2.7/10

improving · -0.9 vs previous 14 d

Pessimism score

Daily log

3.7/10

improving · -0.3 vs previous 14 d

Sleep quality

Wearable

48.2/100

improving · +5.5 vs previous 14 d

Libido

Daily log

5.4/10

improving · +0.5 vs previous 14 d

HRV

Wearable

64 ms

improving · +4.7 vs previous 14 d

Toxicity

Blood

17.2/100

improving · -3.1 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 65 from the failing basin, 49 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +10.9
Butyrate producers intact
hidden · steering +7.5
Lactose (supports)
perturbation · steering +5.3
Adherence Support AD-05
intervention · steering +3.4
Protein
supporter · GI -6.2 next day
Lactose
supporter · GI -3.2 next day

Main detractors to watch

Histamine load
perturbation · steering -12.8
FUT2 non-secretor
hidden · steering -10.6
IL6 high-expression variant
hidden · steering -7.3
Alcohol on dosing days
perturbation · steering -1.8
Histamine load
detractor · GI +6.8 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+6.8detractor · 95%
Protein
-6.2supporter · 95%
Lactose
-3.2supporter · 63%
Caffeine
+1.4no signal · 16%
Alcohol
+1.1no signal · 22%
Dietary fat load
-0.7no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.5 · butyrate capacity 74/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 62 ms
Sleep: 7.5 h
Steps: 8,263
Resting HR: 57 bpm

Daily log: GI score 15, nutritional resilience 65, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03369	53%	S18	AD-05	no change	37
P-03158	46%	S17	AD-05	no change	37
P-03104	43%	S14	AD-05	no change	27
P-03122	43%	S13	AD-05	no change	40
P-03380	43%	S16	AD-05	improved	34
P-03204	41%	S16	AD-05	improved	48
P-03129	40%	S18	AD-05	no change	32
P-03424	40%	S12	AD-05	improved	41
P-03111	38%	S07	AD-05	no change	48
P-03441	37%	S19	AD-05	improved	37
P-03351	35%	S07	AD-05	no change	51
P-03105	30%	S12	AD-05	no change	60