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Patient P-03040

Synthetic patientONX-7 · Day 96 · 65–74 · M · baseline S03Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S03
  2. Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • Nutritional resilience+5
  • Inflammatory activity+4
  • Toxicity-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.4/10
    stable · +0.0 vs previous 14 d
    Stress level
    Daily log
    4.5/10
    stable · +0.0 vs previous 14 d
    Pessimism score
    Daily log
    4.6/10
    stable · +0.0 vs previous 14 d
    Sleep quality
    Wearable
    24.8/100
    improving · +1.7 vs previous 14 d
    Libido
    Daily log
    4.3/10
    stable · -0.2 vs previous 14 d
    HRV
    Wearable
    51.5 ms
    stable · -0.5 vs previous 14 d
    Toxicity
    Blood
    20/100
    stable · -0.1 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 63 from the failing basin, 29 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +5.9
    • Daily walks resumed
      perturbation · steering +3.3
    • Caffeine (supports)
      perturbation · steering +3.3
    • Protein
      supporter · GI -3.1 next day
    • Caffeine
      supporter · GI -2 next day
    Main detractors to watch
    • Low butyrate capacity
      hidden · steering -17.5
    • Low microbial diversity
      hidden · steering -7.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Lactose
      detractor · GI +2.4 next day
    • Dietary fat load
      detractor · GI +2.2 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -3.1supporter · 95%
    • Lactose
      +2.4detractor · 79%
    • Dietary fat load
      +2.2detractor · 66%
    • Caffeine
      -2supporter · 69%
    • Histamine load
      +1.4no signal · 38%
    • Alcohol
      +0.5no signal · 16%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↑45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.4 h, below personal baseline
    • Autonomic recovery ↑40
      • Wearable2,863 steps/day
      • WearableShort sleep window
    • Butyrate / short-chain fatty acid production ↓35
      • MicrobiomeButyrate capacity 29/100
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.5 · butyrate capacity 29/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    50 ms
    Sleep
    5.9 h
    Steps
    2,945
    Resting HR
    74 bpm
    Daily log: GI score 24, nutritional resilience 63, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0344248%S11DT-01improved51
    P-0317947%S05GI-04improved52
    P-0340846%S09HY-01improved53
    P-0314445%S16HY-01improved52
    P-0319345%S13DT-01improved53
    P-0321545%S16HY-01improved44
    P-0324445%S08DT-01improved53
    P-0317843%S11GI-04improved54
    P-0321343%S02DT-01improved59
    P-0325543%S01HY-01improved53
    P-0337543%S09DT-01improved52
    P-0331742%S08HY-01improved45