Patient P-03057

Synthetic patientONX-7 · Day 145 · 45–54 · F · baseline S14Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

31%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S14
Day 63 NP-02 recommended — Dietary Support Protocol NP-02
Day 64 Patient accepted — Started NP-02 in the companion
Day 74 GI symptom burden −15% vs expected — Dietary Support Protocol NP-02
Day 80 Tolerance state changed — Unstable → Improving

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Toxicity-14
Treatment adherence+7
GI instability+6
Inflammatory activity+4

What helped?

Dietary Support Protocol NP-02Day 63
Result: symptom burden −15%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

5.3/10

stable · -0.1 vs previous 14 d

Stress level

Daily log

5.1/10

worsening · +0.4 vs previous 14 d

Pessimism score

Daily log

4.2/10

improving · -0.2 vs previous 14 d

Sleep quality

Wearable

40.5/100

worsening · -2.4 vs previous 14 d

Libido

Daily log

4.8/10

worsening · -0.3 vs previous 14 d

HRV

Wearable

40.6 ms

stable · -0.5 vs previous 14 d

Toxicity

Blood

18.4/100

stable · +0.7 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 71 from the failing basin, 17 from restoration.

Good elements to keep

Dietary Support Protocol NP-02
intervention · steering +23.7
Butyrate producers intact
hidden · steering +7.5
Protein (supports)
perturbation · steering +6.6
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -4 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Low microbial diversity
hidden · steering -7.7
Bacteroides fragilis elevated
hidden · steering -7.4
Lactose
perturbation · steering -4.8
Lactose
detractor · GI +2.6 next day
Caffeine
detractor · GI +2.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4supporter · 95%
Lactose
+2.6detractor · 82%
Caffeine
+2.4detractor · 88%
Histamine load
+1.1no signal · 29%
Alcohol
-0.2no signal · 15%
Dietary fat load
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓45
- WearableResting HR 75 bpm
- WearableShort sleep window
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.9 · butyrate capacity 74/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 45 ms
Sleep: 6.0 h
Steps: 4,367
Resting HR: 75 bpm

Daily log: GI score 25, nutritional resilience 62, adherence 99.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03482	48%	S05	AD-05	no change	67
P-03105	44%	S12	AD-05	no change	60
P-03204	36%	S16	AD-05	improved	48
P-03111	33%	S07	AD-05	no change	48
P-03187	33%	S12	AD-05	no change	80
P-03351	32%	S07	AD-05	no change	51
P-03424	32%	S12	AD-05	improved	41
P-03380	30%	S16	AD-05	improved	34
P-03122	29%	S13	AD-05	no change	40
P-03208	38%	S02	BR-03	improved	57
P-03277	34%	S14	BR-03	improved	41
P-03308	30%	S04	BR-03	improved	39