Patient P-03062
Therapy response
Declining
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
10%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S11
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- Toxicity+12
- GI instability-11
- Nutritional resilience+9
- Inflammatory activity-4
- Treatment adherence-4
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 41/100
- MicrobiomeF. prausnitzii depleted
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Inflammatory signalling ↓25
- DNAIL6 -174 variant raises baseline inflammatory tone
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.3 · butyrate capacity 41/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 60 ms
- Sleep
- 7.3 h
- Steps
- 9,589
- Resting HR
- 60 bpm
Daily log: GI score 16, nutritional resilience 67, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03369 | 43% | S18 | AD-05 | no change | 37 |
| P-03204 | 42% | S16 | AD-05 | improved | 48 |
| P-03034 | 41% | S14 | AD-05 | no change | 30 |
| P-03380 | 40% | S16 | AD-05 | improved | 34 |
| P-03424 | 40% | S12 | AD-05 | improved | 41 |
| P-03122 | 39% | S13 | AD-05 | no change | 40 |
| P-03105 | 38% | S12 | AD-05 | no change | 60 |
| P-03158 | 38% | S17 | AD-05 | no change | 37 |
| P-03111 | 37% | S07 | AD-05 | no change | 48 |
| P-03129 | 37% | S18 | AD-05 | no change | 32 |
| P-03351 | 37% | S07 | AD-05 | no change | 51 |
| P-03441 | 37% | S19 | AD-05 | improved | 37 |