Patient P-03103

Synthetic patientONX-7 · Day 92 · 75+ · F · baseline S14Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Favorable

GI state

Stable

Inflammatory state

Improving

Nutritional resilience

Stable

Discontinuation risk

59%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S14
Day 39 NP-02 recommended — Dietary Support Protocol NP-02
Day 40 Patient accepted — Started NP-02 in the companion
Day 50 No meaningful change — Dietary Support Protocol NP-02
Day 66 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 71 GI-04 recommended — GI Support Protocol GI-04
Day 72 Patient accepted — Started GI-04 in the companion
Day 80 GI symptom burden −36% vs expected — GI Support Protocol GI-04
Day 86 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 66.

Primary contributors, last 14 days

Treatment adherence-21
Inflammatory activity-6
GI instability+4
Toxicity-3
Nutritional resilience-2

What helped?

Dietary Support Protocol NP-02Day 39
Result: no meaningful change
GI Support Protocol GI-04Day 71
Result: symptom burden −36%

LIFE OS recommendation

Clinician Review CR-01

83%

probability of meaningful tolerance improvement

284 similar trajectories
100% showed improvement
median effect visible after 5 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

4.1/10

improving · +0.3 vs previous 14 d

Stress level

Daily log

6.9/10

improving · -0.5 vs previous 14 d

Pessimism score

Daily log

5.7/10

stable · +0.0 vs previous 14 d

Sleep quality

Wearable

26.3/100

improving · +5.5 vs previous 14 d

Libido

Daily log

2.8/10

improving · +0.2 vs previous 14 d

HRV

Wearable

29.1 ms

improving · +1.5 vs previous 14 d

Toxicity

Blood

36/100

stable · -1.0 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 53 from the failing basin, 36 from restoration.

Good elements to keep

GI Support Protocol GI-04
intervention · steering +34.7
Protein (supports)
perturbation · steering +9.8
Dietary Support Protocol NP-02
intervention · steering +7.7
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -6.2 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Dietary fat load
perturbation · steering -12.1
FUT2 non-secretor
hidden · steering -10.6
Lactose
perturbation · steering -10.4
Dietary fat load
detractor · GI +6.1 next day
Lactose
detractor · GI +5.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-6.2supporter · 95%
Dietary fat load
+6.1detractor · 95%
Lactose
+5.3detractor · 95%
Histamine load
+4.3detractor · 95%
Alcohol
-1.8no signal · 32%
Caffeine
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 42
- WearableHRV 29 ms, trending down
Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 24/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
Mucosal barrier integrity ↓70
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.7 h, below personal baseline
Autonomic recovery ↓45
- WearableResting HR 77 bpm
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.6 · butyrate capacity 24/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 5.5 h
Steps: 6,600
Resting HR: 74 bpm

Daily log: GI score 44, nutritional resilience 46, adherence 62.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03365	47%	S14	NP-02	improved	46
P-03279	37%	S14	GI-04	improved	57
P-03289	37%	S03	SC-12	improved	54
P-03031	32%	S16	CR-01	improved	49
P-03382	31%	S01	GI-04	improved	56
P-03465	31%	S17	CR-01	improved	65
P-03123	30%	S14	GI-04	improved	50
P-03166	30%	S20	CR-01	improved	62
P-03201	30%	S15	GI-04	improved	68
P-03226	30%	S05	GI-04	improved	43
P-03346	30%	S17	GI-04	improved	71
P-03379	30%	S12	GI-04	improved	51