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Patient P-03104

Synthetic patientONX-7 · Day 139 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S14
  2. Day 26 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 86 AD-05 recommended — Adherence Support AD-05
  4. Day 87 Patient accepted — Started AD-05 in the companion
  5. Day 92 No meaningful change — Adherence Support AD-05

What changed?

Trajectory began diverging from predicted response on Day 26.

Primary contributors, last 14 days
  • Toxicity+9
  • GI instability-5
  • Nutritional resilience-3
  • Treatment adherence+3

What helped?

  • Adherence Support AD-05Day 86
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
6.9/10
stable · -0.0 vs previous 14 d
Stress level
Daily log
3.4/10
improving · -0.2 vs previous 14 d
Pessimism score
Daily log
4.6/10
improving · -0.2 vs previous 14 d
Sleep quality
Wearable
79.1/100
stable · +2.3 vs previous 14 d
Libido
Daily log
4.7/10
improving · +0.3 vs previous 14 d
HRV
Wearable
71.7 ms
stable · +1.1 vs previous 14 d
Toxicity
Blood
17.4/100
worsening · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 75 from the failing basin, 51 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -6.5 next day on high-intake days · n 22
Would not help
  • AD-05 Adherence Support
    already tried, no meaningful change
  • Keep histamine low
    GI +6.8 next day on high-intake days · n 20
  • Keep caffeine low
    GI +6.1 next day on high-intake days · n 16
  • Keep alcohol low
    GI +5.5 next day on high-intake days · n 14
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +6.8detractor · 95%
  • Protein
    -6.5supporter · 95%
  • Caffeine
    +6.1detractor · 95%
  • Alcohol
    +5.5detractor · 95%
  • Lactose
    +3.7detractor · 71%
  • Dietary fat load
    +0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓60
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3.3 · butyrate capacity 78/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
65 ms
Sleep
7.8 h
Steps
9,491
Resting HR
60 bpm
Daily log: GI score 11, nutritional resilience 66, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Keep fibre steady; no new sources this week
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0342646%S18BR-03improved27
P-0330741%S03ME-01improved17
P-0323540%S13GI-04improved29
P-0337339%S17BR-03improved34
P-0301337%S07GI-04improved30
P-0311434%S11DT-01improved48
P-0338034%S16AD-05improved34
P-0327733%S14BR-03improved41
P-0321532%S16HY-01improved44
P-0340832%S09HY-01improved53
P-0342432%S12AD-05improved41
P-0344232%S11DT-01improved51