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Patient P-03114

Synthetic patientONX-7 · Day 150 · 25–34 · M · baseline S11Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
6%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S11
  2. Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 18 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 19 Patient accepted — Started DT-01 in the companion
  5. Day 24 GI symptom burden −24% vs expected — Dosing / Timing Recommendation DT-01
  6. Day 30 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 13.

Primary contributors, last 14 days
  • GI instability-12
  • Nutritional resilience+10
  • Toxicity-9
  • Inflammatory activity-6

What helped?

  • Dosing / Timing Recommendation DT-01Day 18
    Result: symptom burden −24%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
6.4/10
stable · -0.1 vs previous 14 d
Stress level
Daily log
2.3/10
stable · -0.1 vs previous 14 d
Pessimism score
Daily log
2.8/10
stable · -0.0 vs previous 14 d
Sleep quality
Wearable
53.8/100
stable · +0.5 vs previous 14 d
Libido
Daily log
6/10
stable · +0.0 vs previous 14 d
HRV
Wearable
74.5 ms
improving · +3.3 vs previous 14 d
Toxicity
Blood
8.3/100
improving · -1.4 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 78 from the failing basin, 31 from restoration.

Good elements to keep
  • Dosing / Timing Recommendation DT-01
    intervention · steering +21.2
  • Protein (supports)
    perturbation · steering +7.1
  • Protein
    supporter · GI -4 next day
Main detractors to watch
  • Low butyrate capacity
    hidden · steering -17.5
  • Poor metabolizer
    hidden · steering -12.7
  • Low microbial diversity
    hidden · steering -7.7
  • Bacteroides fragilis elevated
    hidden · steering -7.4
  • Dietary fat load
    detractor · GI +3.7 next day
  • Caffeine
    detractor · GI +3.1 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -4supporter · 95%
  • Dietary fat load
    +3.7detractor · 95%
  • Caffeine
    +3.1detractor · 95%
  • Lactose
    +3detractor · 95%
  • Histamine load
    -0.4no signal · 15%
  • Alcohol
    +0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑75
    • DNACYP2D6 poor metabolizer → higher exposure
    • DNADPYD *2A → slower clearance
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 37/100
    • MicrobiomeF. prausnitzii depleted
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • DPYD *2A heterozygous
    Slower drug clearance
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 2.4 · butyrate capacity 37/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
69 ms
Sleep
7.0 h
Steps
4,504
Resting HR
72 bpm
Daily log: GI score 13, nutritional resilience 73, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0312238%S13AD-05no change40
P-0303436%S14AD-05no change30
P-0336936%S18AD-05no change37
P-0315835%S17AD-05no change37
P-0342435%S12AD-05improved41
P-0344135%S19AD-05improved37
P-0310434%S14AD-05no change27
P-0310534%S12AD-05no change60
P-0320434%S16AD-05improved48
P-0335134%S07AD-05no change51
P-0338034%S16AD-05improved34
P-0312933%S18AD-05no change32