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Patient P-03144

Synthetic patientONX-7 · Day 144 · 45–54 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S16
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 18 HY-01 recommended — Hydration Protocol HY-01
  4. Day 19 Patient accepted — Started HY-01 in the companion
  5. Day 23 GI symptom burden −30% vs expected — Hydration Protocol HY-01
  6. Day 29 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • Nutritional resilience+8
  • Treatment adherence-8
  • Toxicity+5
  • GI instability-4

What helped?

  • Hydration Protocol HY-01Day 18
    Result: symptom burden −30%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
4.8/10
improving · +0.3 vs previous 14 d
Stress level
Daily log
4.9/10
improving · -0.4 vs previous 14 d
Pessimism score
Daily log
4.4/10
improving · -0.2 vs previous 14 d
Sleep quality
Wearable
25.6/100
stable · +0.7 vs previous 14 d
Libido
Daily log
4.2/10
improving · +0.5 vs previous 14 d
HRV
Wearable
34.8 ms
stable · +1.1 vs previous 14 d
Toxicity
Blood
18.3/100
improving · -9.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 69 from the failing basin, 26 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -3.3 next day on high-intake days · n 23
Would not help
  • AD-05 Adherence Support
    only 29% improved among 14 similar
  • Keep fat low
    GI +3.4 next day on high-intake days · n 16
  • Keep caffeine low
    GI +3.1 next day on high-intake days · n 16
  • Keep lactose low
    GI +2.4 next day on high-intake days · n 19
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +3.4detractor · 95%
  • Protein
    -3.3supporter · 95%
  • Caffeine
    +3.1detractor · 95%
  • Lactose
    +2.4detractor · 82%
  • Histamine load
    +0.9no signal · 32%
  • Alcohol
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑75
    • DNACYP2D6 poor metabolizer → higher exposure
    • DNADPYD *2A → slower clearance
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 38/100
    • MicrobiomeF. prausnitzii depleted
  • Autonomic recovery ↑20
    • WearableShort sleep window
  • Inflammatory signalling ↓15
    • WearableHRV 35 ms, trending down
  • Mucosal barrier integrity ↓10
    • WearableSleep 5.6 h, below personal baseline
DNA
Fictional pharmacogenomic panel
  • DPYD *2A heterozygous
    Slower drug clearance
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 2.5 · butyrate capacity 38/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
5.7 h
Steps
9,298
Resting HR
66 bpm
Daily log: GI score 20, nutritional resilience 68, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0320442%S16AD-05improved48
P-0310541%S12AD-05no change60
P-0311138%S07AD-05no change48
P-0342438%S12AD-05improved41
P-0348238%S05AD-05no change67
P-0338037%S16AD-05improved34
P-0336934%S18AD-05no change37
P-0312933%S18AD-05no change32
P-0335133%S07AD-05no change51
P-0303431%S14AD-05no change30
P-0318731%S12AD-05no change80
P-0344131%S19AD-05improved37