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Patient P-03192

Synthetic patientONX-7 · Day 139 · 25–34 · M · baseline S11Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
36%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S11
  2. Day 44 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 44.

Primary contributors, last 14 days
  • GI instability+11
  • Toxicity-7
  • Inflammatory activity+5
  • Nutritional resilience-5

What helped?

No interventions yet.

    LIFE OS recommendation
    Dosing / Timing Recommendation DT-01
    53%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 80% showed improvement
    • median effect visible after 5 days
    View similar patientsSimulateAdd to intervention cohortAll evidence

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    6/10
    stable · -0.0 vs previous 14 d
    Stress level
    Daily log
    5.2/10
    stable · +0.0 vs previous 14 d
    Pessimism score
    Daily log
    4.3/10
    worsening · +0.2 vs previous 14 d
    Sleep quality
    Wearable
    50.9/100
    improving · +3.8 vs previous 14 d
    Libido
    Daily log
    5.1/10
    stable · +0.0 vs previous 14 d
    HRV
    Wearable
    42.1 ms
    improving · +2.7 vs previous 14 d
    Toxicity
    Blood
    12.5/100
    stable · +0.3 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 58 from the failing basin, 30 from restoration.

    Would help
    • DT-01 Dosing / Timing Recommendation
      80% improved among 15 similar · onset 5 d · confidence 51%
    • HY-01 Hydration Protocol
      64% improved among 11 similar · onset 4 d · confidence 51%
    • More protein
      GI -5.7 next day on high-intake days · n 22
    Would not help
    • AD-05 Adherence Support
      only 25% improved among 12 similar
    • Keep lactose low
      GI +3.7 next day on high-intake days · n 22
    • Keep caffeine low
      GI +3.2 next day on high-intake days · n 11
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.7supporter · 95%
    • Lactose
      +3.7detractor · 86%
    • Caffeine
      +3.2detractor · 85%
    • Alcohol
      +1.3no signal · 36%
    • Histamine load
      +1no signal · 22%
    • Dietary fat load
      +0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↑20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.7 · butyrate capacity 62/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    47 ms
    Sleep
    7.9 h
    Steps
    4,890
    Resting HR
    62 bpm
    Daily log: GI score 38, nutritional resilience 54, adherence 90.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0317848%S11GI-04improved54
    P-0325247%S13SC-12improved68
    P-0305744%S14NP-02improved64
    P-0337443%S19ME-01improved55
    P-0325540%S01HY-01improved53
    P-0348439%S07DT-01improved49
    P-0314438%S16HY-01improved52
    P-0317938%S05GI-04improved52
    P-0320438%S16AD-05improved48
    P-0320837%S02BR-03improved57
    P-0332837%S15GI-04improved59
    P-0344237%S11DT-01improved51