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Patient P-03197

Synthetic patientONX-7 · Day 144 · 35–44 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S14
  2. Day 100 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 100.

Primary contributors, last 14 days
  • GI instability-5
  • Inflammatory activity-3
  • Nutritional resilience-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.7/10
    stable · +0.1 vs previous 14 d
    Stress level
    Daily log
    3.7/10
    stable · +0.1 vs previous 14 d
    Pessimism score
    Daily log
    4.1/10
    improving · -0.3 vs previous 14 d
    Sleep quality
    Wearable
    58.8/100
    stable · -1.6 vs previous 14 d
    Libido
    Daily log
    4.8/10
    stable · +0.1 vs previous 14 d
    HRV
    Wearable
    46.3 ms
    stable · +0.8 vs previous 14 d
    Toxicity
    Blood
    17.1/100
    stable · +0.5 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 76 from the failing basin, 37 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein (supports)
      perturbation · steering +7.4
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -4.2 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • FUT2 non-secretor
      hidden · steering -10.6
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Caffeine
      detractor · GI +3.8 next day
    • Histamine load
      detractor · GI +3.2 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -4.2supporter · 95%
    • Caffeine
      +3.8detractor · 95%
    • Histamine load
      +3.2detractor · 95%
    • Lactose
      +2.3detractor · 66%
    • Alcohol
      +1.9detractor · 65%
    • Dietary fat load
      +1no signal · 28%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑75
      • DNACYP2D6 poor metabolizer → higher exposure
      • DNADPYD *2A → slower clearance
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 68/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    43 ms
    Sleep
    7.1 h
    Steps
    5,396
    Resting HR
    57 bpm
    Daily log: GI score 13, nutritional resilience 66, adherence 85.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0342451%S12AD-05improved41
    P-0338049%S16AD-05improved34
    P-0327748%S14BR-03improved41
    P-0337344%S17BR-03improved34
    P-0321542%S16HY-01improved44
    P-0320441%S16AD-05improved48
    P-0323341%S19DT-01improved47
    P-0323539%S13GI-04improved29
    P-0344239%S11DT-01improved51
    P-0314337%S11DT-01improved49
    P-0314437%S16HY-01improved52
    P-0331737%S08HY-01improved45