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Patient P-03202

Synthetic patientONX-7 · Day 143 · 45–54 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
26%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S14
  2. Day 107 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 107.

Primary contributors, last 14 days
  • Toxicity-9
  • Inflammatory activity-7
  • Treatment adherence-5
  • Nutritional resilience+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    6/10
    improving · +0.4 vs previous 14 d
    Stress level
    Daily log
    4.5/10
    stable · -0.1 vs previous 14 d
    Pessimism score
    Daily log
    4.1/10
    improving · -0.3 vs previous 14 d
    Sleep quality
    Wearable
    50.9/100
    improving · +3.5 vs previous 14 d
    Libido
    Daily log
    5.2/10
    stable · -0.0 vs previous 14 d
    HRV
    Wearable
    53.4 ms
    stable · +0.3 vs previous 14 d
    Toxicity
    Blood
    10.5/100
    improving · -1.7 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 67 from the failing basin, 34 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Poor-sleep week
      perturbation · steering -3
    • Histamine load
      detractor · GI +1.9 next day
    • Lactose
      detractor · GI +1.8 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +1.9detractor · 77%
    • Lactose
      +1.8detractor · 70%
    • Protein
      -1no signal · 38%
    • Dietary fat load
      +0.4no signal · 18%
    • Alcohol
      -0.4no signal · 15%
    • Caffeine
      -0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↓25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.9 · butyrate capacity 56/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    56 ms
    Sleep
    7.2 h
    Steps
    7,718
    Resting HR
    63 bpm
    Daily log: GI score 21, nutritional resilience 68, adherence 80.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0327752%S14BR-03improved41
    P-0320447%S16AD-05improved48
    P-0342445%S12AD-05improved41
    P-0337344%S17BR-03improved34
    P-0338044%S16AD-05improved34
    P-0314339%S11DT-01improved49
    P-0323539%S13GI-04improved29
    P-0326839%S15DT-01improved56
    P-0344239%S11DT-01improved51
    P-0323338%S19DT-01improved47
    P-0311437%S11DT-01improved48
    P-0321537%S16HY-01improved44