Patient P-03226
Therapy response
Stable
Tolerance
Favorable
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
51%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S05
- Day 57 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 69 GI-04 recommended — GI Support Protocol GI-04
- Day 70 Patient accepted — Started GI-04 in the companion
- Day 78 GI symptom burden −33% vs expected — GI Support Protocol GI-04
- Day 84 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 57.
Primary contributors, last 14 days
- Inflammatory activity-5
- GI instability-4
What helped?
- GI Support Protocol GI-04Day 69Result: symptom burden −33%
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 63% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.1/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.8/10
stable · -0.1 vs previous 14 d
Pessimism score
Daily log6/10
stable · -0.2 vs previous 14 d
Sleep quality
Wearable39.6/100
improving · +5.2 vs previous 14 d
Libido
Daily log3.1/10
improving · +0.2 vs previous 14 d
HRV
Wearable27.2 ms
stable · +1.1 vs previous 14 d
Toxicity
Blood34.4/100
stable · -0.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 34 from the failing basin, 54 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +53.6
- Protein (supports)perturbation · steering +7.2
- Proteinsupporter · GI -4.6 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Dietary fat loadperturbation · steering -7.6
- Bacteroides fragilis elevatedhidden · steering -7.4
- Dietary fat loaddetractor · GI +4.7 next day
- Lactosedetractor · GI +4.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.7detractor · 95%
- Protein-4.6supporter · 95%
- Lactose+4.5detractor · 95%
- Histamine load+3.6detractor · 95%
- Caffeine-0.8no signal · 20%
- Alcohol+0.7no signal · 19%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 52 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 23/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 46
- WearableHRV 27 ms, trending down
- Autonomic recovery ↓25
- WearableResting HR 72 bpm
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.2 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 32 ms
- Sleep
- 7.1 h
- Steps
- 6,859
- Resting HR
- 73 bpm
Daily log: GI score 52, nutritional resilience 47, adherence 54.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03159 | 50% | S14 | GI-04 | improved | 37 |
| P-03090 | 45% | S02 | GI-04 | improved | 48 |
| P-03300 | 42% | S14 | GI-04 | improved | 46 |
| P-03037 | 40% | S14 | NP-02 | improved | 43 |
| P-03323 | 40% | S14 | GI-04 | improved | 48 |
| P-03003 | 39% | S08 | SC-12 | improved | 53 |
| P-03123 | 39% | S14 | GI-04 | improved | 50 |
| P-03146 | 39% | S14 | GI-04 | improved | 53 |
| P-03049 | 38% | S14 | GI-04 | improved | 49 |
| P-03070 | 38% | S14 | GI-04 | improved | 51 |
| P-03081 | 38% | S10 | GI-04 | improved | 53 |
| P-03145 | 38% | S14 | GI-04 | improved | 51 |