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Patient P-03229

Synthetic patientONX-7 · Day 135 · 45–54 · M · baseline S13Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
16%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S13
  2. Day 32 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 32.

Primary contributors, last 14 days
  • Inflammatory activity-19
  • Toxicity-18
  • GI instability-10
  • Treatment adherence-7
  • Nutritional resilience+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    6.1/10
    improving · +1.2 vs previous 14 d
    Stress level
    Daily log
    3.6/10
    improving · -1.0 vs previous 14 d
    Pessimism score
    Daily log
    4.1/10
    improving · -0.8 vs previous 14 d
    Sleep quality
    Wearable
    44.4/100
    improving · +8.6 vs previous 14 d
    Libido
    Daily log
    5.3/10
    improving · +0.7 vs previous 14 d
    HRV
    Wearable
    72.4 ms
    improving · +4.7 vs previous 14 d
    Toxicity
    Blood
    3.6/100
    improving · -9.2 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 68 from the failing basin, 44 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein (supports)
      perturbation · steering +7.2
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -4.7 next day
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Rapid metabolizer
      hidden · steering -8
    • Histamine load
      perturbation · steering -7.5
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Histamine load
      detractor · GI +4.6 next day
    • Lactose
      detractor · GI +4 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -4.7supporter · 95%
    • Histamine load
      +4.6detractor · 95%
    • Lactose
      +4detractor · 95%
    • Dietary fat load
      -1.8no signal · 38%
    • Caffeine
      +1.5no signal · 36%
    • Alcohol
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓70
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.8 h, below personal baseline
    • Autonomic recovery ↑40
      • Wearable3,418 steps/day
      • WearableShort sleep window
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.1 · butyrate capacity 46/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    70 ms
    Sleep
    6.1 h
    Steps
    3,447
    Resting HR
    67 bpm
    Daily log: GI score 23, nutritional resilience 64, adherence 79.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0310441%S14AD-05no change27
    P-0303438%S14AD-05no change30
    P-0336938%S18AD-05no change37
    P-0312236%S13AD-05no change40
    P-0315833%S17AD-05no change37
    P-0312932%S18AD-05no change32
    P-0320431%S16AD-05improved48
    P-0338031%S16AD-05improved34
    P-0342431%S12AD-05improved41
    P-0311130%S07AD-05no change48
    P-0344130%S19AD-05improved37
    P-0335129%S07AD-05no change51