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Patient P-03248

Synthetic patientONX-7 · Day 121 · 55–64 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S18
  2. Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • GI instability-12
  • Nutritional resilience+6
  • Inflammatory activity-4
  • Treatment adherence+3
  • Toxicity-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.4/10
    worsening · -0.2 vs previous 14 d
    Stress level
    Daily log
    3.3/10
    worsening · +0.1 vs previous 14 d
    Pessimism score
    Daily log
    4.3/10
    worsening · +0.4 vs previous 14 d
    Sleep quality
    Wearable
    43.7/100
    worsening · -4.5 vs previous 14 d
    Libido
    Daily log
    5.4/10
    stable · +0.1 vs previous 14 d
    HRV
    Wearable
    70 ms
    stable · +1.9 vs previous 14 d
    Toxicity
    Blood
    8.8/100
    improving · -2.5 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 67 from the failing basin, 51 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +9.9
    • Butyrate producers intact
      hidden · steering +7.5
    • Dietary fat load (supports)
      perturbation · steering +3.2
    • Protein
      supporter · GI -5.9 next day
    • Dietary fat load
      supporter · GI -2.4 next day
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Alcohol
      perturbation · steering -8.8
    • Histamine load
      perturbation · steering -7.5
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Alcohol
      detractor · GI +4.7 next day
    • Histamine load
      detractor · GI +4 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.9supporter · 95%
    • Alcohol
      +4.7detractor · 95%
    • Histamine load
      +4detractor · 95%
    • Lactose
      +3.9detractor · 95%
    • Dietary fat load
      -2.4supporter · 55%
    • Caffeine
      +1no signal · 24%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery ↑45
      • WearableResting HR 72 bpm
      • WearableShort sleep window
    • Mucosal barrier integrity ↓40
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • WearableSleep 5.9 h, below personal baseline
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.3 · butyrate capacity 52/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    65 ms
    Sleep
    6.4 h
    Steps
    5,587
    Resting HR
    75 bpm
    Daily log: GI score 19, nutritional resilience 64, adherence 89.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0310447%S14AD-05no change27
    P-0303439%S14AD-05no change30
    P-0336938%S18AD-05no change37
    P-0315836%S17AD-05no change37
    P-0312233%S13AD-05no change40
    P-0338032%S16AD-05improved34
    P-0312931%S18AD-05no change32
    P-0342431%S12AD-05improved41
    P-0320430%S16AD-05improved48
    P-0344129%S19AD-05improved37
    P-0311128%S07AD-05no change48
    P-0335127%S07AD-05no change51