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Patient P-03255

Synthetic patientONX-7 · Day 145 · 45–54 · M · baseline S01Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
42%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S01
  2. Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 18 HY-01 recommended — Hydration Protocol HY-01
  4. Day 19 Patient accepted — Started HY-01 in the companion
  5. Day 23 GI symptom burden −20% vs expected — Hydration Protocol HY-01
  6. Day 29 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days
  • GI instability+17
  • Toxicity+17
  • Nutritional resilience-15
  • Inflammatory activity+14
  • Treatment adherence-9

What helped?

  • Hydration Protocol HY-01Day 18
    Result: symptom burden −20%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
5.5/10
worsening · -0.4 vs previous 14 d
Stress level
Daily log
4.1/10
worsening · +0.6 vs previous 14 d
Pessimism score
Daily log
4.6/10
worsening · +0.3 vs previous 14 d
Sleep quality
Wearable
38.3/100
worsening · -8.6 vs previous 14 d
Libido
Daily log
3.9/10
worsening · -0.3 vs previous 14 d
HRV
Wearable
37.8 ms
worsening · -5.7 vs previous 14 d
Toxicity
Blood
25.6/100
stable · +0.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 62 from the failing basin, 28 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -6.2 next day on high-intake days · n 21
Would not help
  • AD-05 Adherence Support
    only 23% improved among 13 similar
  • Keep fat low
    GI +6.1 next day on high-intake days · n 24
  • Keep histamine low
    GI +6.1 next day on high-intake days · n 18
  • Keep lactose low
    GI +5.1 next day on high-intake days · n 19
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -6.2supporter · 95%
  • Dietary fat load
    +6.1detractor · 95%
  • Histamine load
    +6.1detractor · 95%
  • Lactose
    +5.1detractor · 95%
  • Alcohol
    +0.8no signal · 15%
  • Caffeine
    -0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓60
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 22/100
    • MicrobiomeF. prausnitzii depleted
  • Autonomic recovery ↓20
    • Wearable3,853 steps/day
  • Inflammatory signalling ↑15
    • WearableHRV 38 ms, trending down
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Intermediate metabolizer
    Expected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 22/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
44 ms
Sleep
6.6 h
Steps
5,312
Resting HR
68 bpm
Daily log: GI score 28, nutritional resilience 55, adherence 91.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0317950%S05GI-04improved52
P-0347150%S08——54
P-0332848%S15GI-04improved59
P-0348448%S07DT-01improved49
P-0338947%S01——50
P-0324446%S08DT-01improved53
P-0342046%S08——59
P-0321445%S18——68
P-0314444%S16HY-01improved52
P-0319844%S11——52
P-0330644%S02HY-01no change59
P-0304043%S03——51