500 patients67,039 observations150 daysLIVE
← Patients

Patient P-03280

Synthetic patientONX-7 · Day 145 · 65–74 · M · baseline S13Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
70%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S13
  2. Day 75 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 75.

Primary contributors, last 14 days
  • Toxicity+12
  • Inflammatory activity+10
  • GI instability+8
  • Nutritional resilience-4
  • Treatment adherence-2

What helped?

No interventions yet.

    LIFE OS recommendation
    GI Support Protocol GI-04
    67%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 83% showed improvement
    • median effect visible after 8 days
    View similar patientsSimulateAdd to intervention cohortAll evidence

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    2.9/10
    worsening · -0.5 vs previous 14 d
    Stress level
    Daily log
    6.7/10
    worsening · +0.6 vs previous 14 d
    Pessimism score
    Daily log
    6.2/10
    worsening · +0.6 vs previous 14 d
    Sleep quality
    Wearable
    25.8/100
    worsening · -2.7 vs previous 14 d
    Libido
    Daily log
    1.9/10
    worsening · -0.7 vs previous 14 d
    HRV
    Wearable
    30.3 ms
    worsening · -3.4 vs previous 14 d
    Toxicity
    Blood
    50.1/100
    worsening · +15.0 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 34 from the failing basin, 67 from restoration.

    Would help
    • GI-04 GI Support Protocol
      74% improved among 34 similar · onset 8 d · confidence 66%
    • ME-01 Monitoring Escalation
      100% improved among 11 similar · onset 3 d · confidence 73%
    • DT-01 Dosing / Timing Recommendation
      82% improved among 11 similar · onset 5 d · confidence 73%
    • More protein
      GI -4.5 next day on high-intake days · n 13
    • More lactose
      GI -3.1 next day on high-intake days · n 11
    Would not help
    • AD-05 Adherence Support
      only 25% improved among 8 similar
    • Keep fat low
      GI +4.9 next day on high-intake days · n 24
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Dietary fat load
      +4.9detractor · 95%
    • Protein
      -4.5supporter · 95%
    • Lactose
      -3.1supporter · 58%
    • Caffeine
      +0.8no signal · 19%
    • Alcohol
      -0.3no signal · 15%
    • Histamine load
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Butyrate / short-chain fatty acid production ↓55
      • MicrobiomeButyrate capacity 38/100
      • Daily logFibre intake low in recent food logs
    • Mucosal barrier integrity ↓50
      • MicrobiomeAkkermansia low → thinner mucus layer
      • Daily logGI symptom score 67 and rising
    • Autonomic recovery ↓45
      • WearableResting HR 78 bpm
      • Wearable1,825 steps/day
    • Inflammatory signalling ↑40
      • BloodInflammatory load index 62
      • WearableHRV 30 ms, trending down
    • Drug metabolism and exposure ↑20
      • BloodToxicity index 50
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2 · butyrate capacity 38/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    35 ms
    Sleep
    6.8 h
    Steps
    779
    Resting HR
    79 bpm
    Daily log: GI score 67, nutritional resilience 37, adherence 65.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
    • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Track each bowel movement today: time, stool form, urgency, overnight waking
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • Electrolyte solution, one sachet after any loose stool
    • Fictional demo item: oral nutrition supplement with lunch

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0318349%S03——54
    P-0309947%S17CR-01improved55
    P-0344447%S17——62
    P-0335245%S19——59
    P-0322544%S19GI-04improved50
    P-0300443%S03——56
    P-0308043%S09——62
    P-0319143%S19GI-04improved51
    P-0316642%S20CR-01improved62
    P-0338441%S01——55
    P-0345141%S08——62
    P-0303140%S16CR-01improved49