Patient P-03328

Synthetic patientONX-7 · Day 144 · 65–74 · F · baseline S15Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S15
Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 18 GI-04 recommended — GI Support Protocol GI-04
Day 19 Patient accepted — Started GI-04 in the companion
Day 27 GI symptom burden −11% vs expected — GI Support Protocol GI-04
Day 33 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days

GI instability-14
Nutritional resilience+6
Toxicity+5
Treatment adherence-3

What helped?

GI Support Protocol GI-04Day 18
Result: symptom burden −11%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.5/10

worsening · -0.8 vs previous 14 d

Stress level

Daily log

4.2/10

worsening · +0.8 vs previous 14 d

Pessimism score

Daily log

3.8/10

worsening · +0.2 vs previous 14 d

Sleep quality

Wearable

42/100

worsening · -6.4 vs previous 14 d

Libido

Daily log

4.7/10

worsening · -0.5 vs previous 14 d

HRV

Wearable

36.1 ms

worsening · -4.4 vs previous 14 d

Toxicity

Blood

17.7/100

stable · +0.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 74 from the failing basin, 19 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -6.9 next day on high-intake days · n 18

Would not help

AD-05 Adherence Support
only 23% improved among 13 similar
Keep fat low
GI +5.1 next day on high-intake days · n 22
Keep lactose low
GI +4.8 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-6.9supporter · 95%
Dietary fat load
+5.1detractor · 95%
Lactose
+4.8detractor · 95%
Histamine load
+1no signal · 19%
Caffeine
+0.7no signal · 15%
Alcohol
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 36 ms, trending down
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 39/100
Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3 · butyrate capacity 39/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 6.6 h
Steps: 3,072
Resting HR: 65 bpm

Daily log: GI score 18, nutritional resilience 64, adherence 91.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03105	38%	S12	AD-05	no change	60
P-03482	38%	S05	AD-05	no change	67
P-03424	37%	S12	AD-05	improved	41
P-03111	36%	S07	AD-05	no change	48
P-03204	36%	S16	AD-05	improved	48
P-03380	33%	S16	AD-05	improved	34
P-03158	31%	S17	AD-05	no change	37
P-03187	31%	S12	AD-05	no change	80
P-03351	31%	S07	AD-05	no change	51
P-03369	31%	S18	AD-05	no change	37
P-03122	30%	S13	AD-05	no change	40
P-03129	30%	S18	AD-05	no change	32