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Patient P-03368

Synthetic patientONX-7 · Day 146 · 65–74 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
37%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S12
  2. Day 54 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 54.

Primary contributors, last 14 days
  • GI instability+14
  • Nutritional resilience-12
  • Inflammatory activity+6
  • Treatment adherence+5
  • Toxicity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5/10
    worsening · -0.4 vs previous 14 d
    Stress level
    Daily log
    5/10
    worsening · +0.2 vs previous 14 d
    Pessimism score
    Daily log
    4.5/10
    stable · -0.0 vs previous 14 d
    Sleep quality
    Wearable
    47.3/100
    worsening · -5.1 vs previous 14 d
    Libido
    Daily log
    3.6/10
    worsening · -0.3 vs previous 14 d
    HRV
    Wearable
    52.9 ms
    stable · -1.5 vs previous 14 d
    Toxicity
    Blood
    19.9/100
    improving · -1.7 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 61 from the failing basin, 27 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -8 next day on high-intake days · n 20
    • More lactose
      GI -3.9 next day on high-intake days · n 15
    Would not help
    • AD-05 Adherence Support
      only 29% improved among 14 similar
    • Keep alcohol low
      GI +6.5 next day on high-intake days · n 23
    • Keep caffeine low
      GI +4.2 next day on high-intake days · n 15
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -8supporter · 95%
    • Alcohol
      +6.5detractor · 95%
    • Caffeine
      +4.2detractor · 95%
    • Lactose
      -3.9supporter · 76%
    • Dietary fat load
      -2.7no signal · 51%
    • Histamine load
      -1.3no signal · 23%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.9 · butyrate capacity 61/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    53 ms
    Sleep
    6.9 h
    Steps
    9,460
    Resting HR
    60 bpm
    Daily log: GI score 32, nutritional resilience 56, adherence 96.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0310559%S12AD-05no change60
    P-0348239%S05AD-05no change67
    P-0320438%S16AD-05improved48
    P-0342436%S12AD-05improved41
    P-0311133%S07AD-05no change48
    P-0335133%S07AD-05no change51
    P-0318732%S12AD-05no change80
    P-0336931%S18AD-05no change37
    P-0338031%S16AD-05improved34
    P-0303430%S14AD-05no change30
    P-0312229%S13AD-05no change40
    P-0312929%S18AD-05no change32