Patient P-03369

Synthetic patientONX-7 · Day 143 · 75+ · F · baseline S18Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S18
Day 90 AD-05 recommended — Adherence Support AD-05
Day 91 Patient accepted — Started AD-05 in the companion
Day 96 No meaningful change — Adherence Support AD-05
Day 100 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 100.

Primary contributors, last 14 days

Toxicity-15
Inflammatory activity-6
Nutritional resilience+5
Treatment adherence+5
GI instability-3

What helped?

Adherence Support AD-05Day 90
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

5.4/10

improving · +0.6 vs previous 14 d

Stress level

Daily log

4/10

improving · -0.7 vs previous 14 d

Pessimism score

Daily log

4.3/10

stable · -0.1 vs previous 14 d

Sleep quality

Wearable

50.4/100

improving · +1.9 vs previous 14 d

Libido

Daily log

4.4/10

improving · +0.4 vs previous 14 d

HRV

Wearable

56.2 ms

improving · +2.9 vs previous 14 d

Toxicity

Blood

13.2/100

improving · -1.5 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 69 from the failing basin, 41 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +8.4
Adherence Support AD-05
intervention · steering +8
Butyrate producers intact
hidden · steering +7.5
Protein
supporter · GI -4.3 next day

Main detractors to watch

FUT2 non-secretor
hidden · steering -10.6
Histamine load
perturbation · steering -7.9
Bacteroides fragilis elevated
hidden · steering -7.4
Lactose
perturbation · steering -6.2
Lactose
detractor · GI +4.5 next day
Histamine load
detractor · GI +4.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Lactose
+4.5detractor · 95%
Histamine load
+4.4detractor · 95%
Protein
-4.3supporter · 95%
Dietary fat load
-0.5no signal · 15%
Caffeine
-0.4no signal · 15%
Alcohol
+0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.8 · butyrate capacity 48/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 53 ms
Sleep: 6.6 h
Steps: 4,619
Resting HR: 63 bpm

Daily log: GI score 18, nutritional resilience 65, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03034	53%	S14	AD-05	no change	30
P-03122	47%	S13	AD-05	no change	40
P-03380	47%	S16	AD-05	improved	34
P-03129	46%	S18	AD-05	no change	32
P-03204	45%	S16	AD-05	improved	48
P-03158	44%	S17	AD-05	no change	37
P-03424	42%	S12	AD-05	improved	41
P-03441	41%	S19	AD-05	improved	37
P-03111	40%	S07	AD-05	no change	48
P-03104	38%	S14	AD-05	no change	27
P-03351	38%	S07	AD-05	no change	51
P-03105	32%	S12	AD-05	no change	60