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Patient P-03372

Synthetic patientONX-7 · Day 148 · 65–74 · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S19
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • Inflammatory activity+4
  • Nutritional resilience-4
  • Toxicity+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    6.6/10
    stable · +0.2 vs previous 14 d
    Stress level
    Daily log
    4.3/10
    improving · -0.3 vs previous 14 d
    Pessimism score
    Daily log
    4/10
    stable · +0.1 vs previous 14 d
    Sleep quality
    Wearable
    54.7/100
    improving · +5.3 vs previous 14 d
    Libido
    Daily log
    4.5/10
    stable · -0.0 vs previous 14 d
    HRV
    Wearable
    30.9 ms
    stable · -0.5 vs previous 14 d
    Toxicity
    Blood
    20.5/100
    improving · -4.6 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 68 from the failing basin, 26 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -6.3 next day on high-intake days · n 25
    Would not help
    • AD-05 Adherence Support
      only 29% improved among 14 similar
    • Keep fat low
      GI +5.4 next day on high-intake days · n 20
    • Keep lactose low
      GI +4.9 next day on high-intake days · n 17
    • Keep histamine low
      GI +4.4 next day on high-intake days · n 23
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -6.3supporter · 95%
    • Dietary fat load
      +5.4detractor · 95%
    • Lactose
      +4.9detractor · 95%
    • Histamine load
      +4.4detractor · 95%
    • Caffeine
      -1.1no signal · 20%
    • Alcohol
      +1.1no signal · 20%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↑35
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 31 ms, trending down
    • Butyrate / short-chain fatty acid production ↓35
      • MicrobiomeButyrate capacity 39/100
    • Drug metabolism and exposure ↑35
      • DNADPYD *2A → slower clearance
    • Autonomic recovery ↓20
      • Wearable2,723 steps/day
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.7 · butyrate capacity 39/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    31 ms
    Sleep
    7.8 h
    Steps
    3,642
    Resting HR
    70 bpm
    Daily log: GI score 21, nutritional resilience 61, adherence 90.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0310540%S12AD-05no change60
    P-0311139%S07AD-05no change48
    P-0348238%S05AD-05no change67
    P-0320437%S16AD-05improved48
    P-0342436%S12AD-05improved41
    P-0338034%S16AD-05improved34
    P-0336933%S18AD-05no change37
    P-0312932%S18AD-05no change32
    P-0335131%S07AD-05no change51
    P-0303430%S14AD-05no change30
    P-0344130%S19AD-05improved37
    P-0312229%S13AD-05no change40