500 patients67,039 observations150 daysLIVE
← Patients

Patient P-03395

Synthetic patientONX-7 · Day 135 · 35–44 · M · baseline S03Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S03
  2. Day 25 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 25.

Primary contributors, last 14 days
  • Toxicity+12
  • GI instability-11
  • Inflammatory activity-7
  • Nutritional resilience+5
  • Treatment adherence+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    6/10
    improving · +0.6 vs previous 14 d
    Stress level
    Daily log
    3.2/10
    improving · -0.5 vs previous 14 d
    Pessimism score
    Daily log
    4.1/10
    improving · -0.3 vs previous 14 d
    Sleep quality
    Wearable
    70.3/100
    improving · +11.9 vs previous 14 d
    Libido
    Daily log
    4.6/10
    improving · +0.6 vs previous 14 d
    HRV
    Wearable
    66.2 ms
    stable · +2.4 vs previous 14 d
    Toxicity
    Blood
    18.5/100
    stable · +0.0 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 67 from the failing basin, 52 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -4 next day on high-intake days · n 18
    Would not help
    • AD-05 Adherence Support
      only 31% improved among 13 similar
    • Keep lactose low
      GI +3.3 next day on high-intake days · n 13
    • Keep histamine low
      GI +2.6 next day on high-intake days · n 23
    • Keep caffeine low
      GI +2.6 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -4supporter · 95%
    • Lactose
      +3.3detractor · 95%
    • Histamine load
      +2.6detractor · 95%
    • Caffeine
      +2.6detractor · 95%
    • Alcohol
      +2.1detractor · 77%
    • Dietary fat load
      -0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity ↓30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery ↑20
      • Wearable3,373 steps/day
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 2.8 · butyrate capacity 65/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    65 ms
    Sleep
    8.1 h
    Steps
    3,889
    Resting HR
    69 bpm
    Daily log: GI score 18, nutritional resilience 69, adherence 87.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0310452%S14AD-05no change27
    P-0303440%S14AD-05no change30
    P-0336937%S18AD-05no change37
    P-0315835%S17AD-05no change37
    P-0312233%S13AD-05no change40
    P-0338032%S16AD-05improved34
    P-0312931%S18AD-05no change32
    P-0342431%S12AD-05improved41
    P-0311130%S07AD-05no change48
    P-0320430%S16AD-05improved48
    P-0344128%S19AD-05improved37
    P-0335127%S07AD-05no change51