Patient P-03431
Therapy response
Favorable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S05
- Day 43 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 44 Patient accepted — Started DT-01 in the companion
- Day 49 GI symptom burden −18% vs expected — Dosing / Timing Recommendation DT-01
- Day 55 Tolerance state changed — Unstable → Improving
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- GI instability+11
- Inflammatory activity+8
- Treatment adherence-5
- Nutritional resilience-4
- Toxicity-2
What helped?
- Dosing / Timing Recommendation DT-01Day 43Result: symptom burden −18%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 4.5 · butyrate capacity 77/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 52 ms
- Sleep
- 7.0 h
- Steps
- 6,527
- Resting HR
- 56 bpm
Daily log: GI score 11, nutritional resilience 70, adherence 95.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03001 | 52% | S04 | CR-01 | improved | 87 |
| P-03018 | 48% | S05 | ME-01 | improved | 84 |
| P-03288 | 48% | S15 | CR-01 | improved | 88 |
| P-03008 | 47% | S16 | SC-12 | improved | 87 |
| P-03140 | 47% | S20 | AD-05 | improved | 79 |
| P-03165 | 43% | S06 | NP-02 | improved | 79 |
| P-03333 | 36% | S14 | SC-12 | improved | 91 |
| P-03449 | 33% | S14 | DT-01 | improved | 79 |
| P-03188 | 31% | S13 | HY-01 | improved | 79 |
| P-03473 | 30% | S07 | DT-01 | improved | 70 |
| P-03208 | 28% | S02 | BR-03 | improved | 57 |
| P-03252 | 28% | S13 | SC-12 | improved | 68 |