700 patients110,866 observations180 daysLIVE
← Patients

Patient P-02045

Synthetic patientMETA-24 · Day 180 · 35–44 · F · baseline S07Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
16%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S07
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • Toxicity-10
  • GI instability-7
  • Inflammatory activity-6
  • Treatment adherence-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    76 min
    worsening · -4.1 vs previous 14 d
    Sleep duration
    Wearable
    8.1 h
    stable · 0.0 vs previous 14 d
    Energy level
    Daily log
    5.8/10
    worsening · -0.4 vs previous 14 d
    Steps
    Wearable
    7,590
    worsening · -592 vs previous 14 d
    GI burden
    Companion
    23.3/100
    worsening · +2.1 vs previous 14 d
    Adherence
    Companion
    90.6 %
    stable · -0.8 vs previous 14 d
    Sleep quality
    Wearable
    78.7/100
    stable · -1.0 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    132 mg/dL
    stable · +0.6 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 67 from the failing basin, 27 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +10.8
    • Protein
      supporter · GI -5.5 next day
    Main detractors to watch
    • Low butyrate capacity
      hidden · steering -17.5
    • Poor metabolizer
      hidden · steering -12.7
    • FUT2 non-secretor
      hidden · steering -10.6
    • Histamine load
      perturbation · steering -9.8
    • Caffeine
      detractor · GI +5.7 next day
    • Histamine load
      detractor · GI +5.6 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Caffeine
      +5.7detractor · 95%
    • Histamine load
      +5.6detractor · 95%
    • Protein
      -5.5supporter · 95%
    • Dietary fat load
      +5detractor · 95%
    • Alcohol
      +4.9detractor · 95%
    • Ultra-processed food
      +4.6detractor · 95%
    • Simple carbohydrates
      +2.2detractor · 60%
    • Insoluble fibre
      +0.9no signal · 20%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Butyrate / short-chain fatty acid production ↓35
      • MicrobiomeButyrate capacity 42/100
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 2 · butyrate capacity 42/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    65 ms
    Sleep
    7.8 h
    Steps
    6,299
    Resting HR
    63 bpm
    Daily log: GI score 23, nutritional resilience 60, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0269755%S07GI-04improved56
    P-0214751%S13GI-04improved58
    P-0247950%S13DT-01improved48
    P-0230348%S15GI-04improved48
    P-0248448%S15GI-04improved49
    P-0268548%S16DT-01improved47
    P-0264547%S02HY-01improved56
    P-0223546%S14DT-01improved50
    P-0233945%S03DT-01improved50
    P-0249445%S09GI-04improved47
    P-0258645%S18DT-01improved56
    P-0260245%S20HY-01improved52