Patient P-02052

Synthetic patientMETA-24 · Day 173 · 65–74 · F · baseline S11Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Deteriorating

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

21%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S11
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 HY-01 recommended — Hydration Protocol HY-01
Day 23 Patient accepted — Started HY-01 in the companion
Day 27 No meaningful change — Hydration Protocol HY-01

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

Nutritional resilience+8
Toxicity+5
GI instability-3
Inflammatory activity+3
Treatment adherence+2

What helped?

Hydration Protocol HY-01Day 22
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

43 min

worsening · -5.9 vs previous 14 d

Sleep duration

Wearable

6 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

5.1/10

worsening · -0.3 vs previous 14 d

Steps

Wearable

5,592

worsening · -486 vs previous 14 d

GI burden

Companion

27.4/100

worsening · +5.9 vs previous 14 d

Adherence

Companion

88.5 %

worsening · -4.8 vs previous 14 d

Sleep quality

Wearable

41/100

worsening · -2.4 vs previous 14 d

Glucose, CGM daily mean

CGM

132 mg/dL

stable · +4.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 58 from the failing basin, 34 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -6 next day on high-intake days · n 25

Would not help

HY-01 Hydration Protocol
already tried, no meaningful change
BR-03 Behavioural Recommendation
only 13% improved among 8 similar
Keep fat low
GI +5.2 next day on high-intake days · n 18
Keep ultra-processed low
GI +4.1 next day on high-intake days · n 16
Keep simple carbs low
GI +3.9 next day on high-intake days · n 16

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-6supporter · 95%
Dietary fat load
+5.2detractor · 95%
Ultra-processed food
+4.1detractor · 95%
Simple carbohydrates
+3.9detractor · 95%
Caffeine
+2.5detractor · 62%
Histamine load
+2.3no signal · 48%
Alcohol
+0.9no signal · 22%
Insoluble fibre
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑45
- WearableResting HR 75 bpm
- WearableShort sleep window
Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.9 · butyrate capacity 30/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 53 ms
Sleep: 5.9 h
Steps: 5,641
Resting HR: 77 bpm

Daily log: GI score 27, nutritional resilience 62, adherence 89.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02274	53%	S15	DT-01	improved	50
P-02339	51%	S03	DT-01	improved	50
P-02223	49%	S20	HY-01	improved	49
P-02484	49%	S15	GI-04	improved	49
P-02479	48%	S13	DT-01	improved	48
P-02685	48%	S16	DT-01	improved	47
P-02538	47%	S02	GI-04	improved	59
P-02033	46%	S06	GI-04	improved	51
P-02235	46%	S14	DT-01	improved	50
P-02303	46%	S15	GI-04	improved	48
P-02645	46%	S02	HY-01	improved	56
P-02037	45%	S04	GI-04	improved	53