Patient P-02064

Synthetic patientMETA-24 · Day 109 · 65–74 · F · baseline S04Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Favorable

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S04
Day 41 SC-12 recommended — Supportive Compound SC-12
Day 42 Patient accepted — Started SC-12 in the companion
Day 48 GI symptom burden −18% vs expected — Supportive Compound SC-12
Day 54 Tolerance state changed — Unstable → Improving
Day 60 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 60.

Primary contributors, last 14 days

Inflammatory activity-10
Toxicity-7
Nutritional resilience+6
Treatment adherence+4

What helped?

Supportive Compound SC-12Day 41
Result: symptom burden −18%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

38 min

improving · +6.4 vs previous 14 d

Sleep duration

Wearable

6.2 h

stable · +0.2 vs previous 14 d

Energy level

Daily log

5.7/10

improving · +0.3 vs previous 14 d

Steps

Wearable

4,246

improving · +707 vs previous 14 d

GI burden

Companion

25/100

improving · -7.2 vs previous 14 d

Adherence

Companion

97.6 %

stable · +1.5 vs previous 14 d

Sleep quality

Wearable

35.7/100

improving · +4.7 vs previous 14 d

Glucose, CGM daily mean

CGM

131 mg/dL

improving · -7.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 73 from the failing basin, 23 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.9 next day on high-intake days · n 20

Would not help

Keep histamine low
GI +7 next day on high-intake days · n 24
Keep ultra-processed low
GI +4.2 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+7detractor · 95%
Protein
-5.9supporter · 95%
Ultra-processed food
+4.2detractor · 88%
Simple carbohydrates
-1.7no signal · 26%
Alcohol
+1.5no signal · 30%
Dietary fat load
-1no signal · 19%
Caffeine
+0.8no signal · 15%
Insoluble fibre
+0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 36 ms, trending down
Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Intermediate metabolizer
Expected exposure

Microbiome

Shannon diversity 4.3 · butyrate capacity 79/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 34 ms
Sleep: 6.9 h
Steps: 4,538
Resting HR: 64 bpm

Daily log: GI score 25, nutritional resilience 65, adherence 98.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02126	44%	S16	DT-01	improved	59
P-02355	43%	S09	GI-04	improved	55
P-02414	41%	S13	HY-01	improved	58
P-02485	41%	S05	HY-01	improved	63
P-02620	41%	S01	HY-01	improved	64
P-02033	40%	S06	GI-04	improved	51
P-02037	40%	S04	GI-04	improved	53
P-02150	40%	S11	HY-01	improved	45
P-02462	40%	S12	DT-01	improved	65
P-02645	40%	S02	HY-01	improved	56
P-02082	39%	S12	NP-02	improved	53
P-02223	39%	S20	HY-01	improved	49