Patient P-02102
Synthetic patientMETA-24 · Day 90 · 55–64 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Unstable
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 65 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 78 GI-04 recommended — GI Support Protocol GI-04
- Day 79 Patient accepted — Started GI-04 in the companion
- Day 87 GI symptom burden −36% vs expected — GI Support Protocol GI-04
- Day 93 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 65.
Primary contributors, last 14 days
- Nutritional resilience-12
- GI instability+7
- Treatment adherence+7
- Inflammatory activity+6
- Toxicity+5
What helped?
- GI Support Protocol GI-04Day 78Result: symptom burden −36%
LIFE OS recommendation
Hydration Protocol HY-01
54%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 70% showed improvement
- median effect visible after 4 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable42 min
worsening · -7.7 vs previous 14 d
Sleep duration
Wearable5.4 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log3.4/10
worsening · -0.9 vs previous 14 d
Steps
Wearable4,239
worsening · -634 vs previous 14 d
GI burden
Companion53.8/100
worsening · +9.4 vs previous 14 d
Adherence
Companion94.3 %
stable · +2.2 vs previous 14 d
Sleep quality
Wearable18.7/100
worsening · -4.3 vs previous 14 d
Glucose, CGM daily mean
CGM155 mg/dL
stable · +4.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 46 from the failing basin, 48 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 8 similar · onset 3 d · confidence 60%
- HY-01 Hydration Protocol70% improved among 10 similar · onset 4 d · confidence 60%
- DT-01 Dosing / Timing Recommendation70% improved among 10 similar · onset 5 d · confidence 60%
- More proteinGI -6.4 next day on high-intake days · n 21
Would not help
- Keep histamine lowGI +5 next day on high-intake days · n 24
- Keep alcohol lowGI +4.5 next day on high-intake days · n 21
- Keep fat lowGI +4.2 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.4supporter · 95%
- Histamine load+5detractor · 95%
- Alcohol+4.5detractor · 95%
- Dietary fat load+4.2detractor · 95%
- Simple carbohydrates+2.6no signal · 55%
- Ultra-processed food+1.5no signal · 35%
- Caffeine+0.8no signal · 18%
- Insoluble fibre+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 54 and rising
- WearableSleep 5.4 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 23/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 80 bpm
- WearableShort sleep window
- Inflammatory signalling ↑40
- BloodInflammatory load index 51
- WearableHRV 22 ms, trending down
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.3 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 23 ms
- Sleep
- 5.8 h
- Steps
- 4,396
- Resting HR
- 79 bpm
Daily log: GI score 54, nutritional resilience 40, adherence 94.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02115 | 43% | S14 | GI-04 | improved | 75 |
| P-02575 | 38% | S14 | ME-01 | improved | 73 |
| P-02298 | 35% | S14 | GI-04 | improved | 65 |
| P-02060 | 33% | S14 | GI-04 | improved | 54 |
| P-02666 | 31% | S14 | ME-01 | improved | 51 |
| P-02334 | 29% | S04 | GI-04 | improved | 66 |
| P-02299 | 28% | S14 | GI-04 | improved | 59 |
| P-02433 | 28% | S07 | GI-04 | improved | 61 |
| P-02459 | 28% | S05 | HY-01 | improved | 52 |
| P-02460 | 28% | S18 | GI-04 | improved | 59 |
| P-02233 | 27% | S16 | CR-01 | improved | 66 |
| P-02508 | 27% | S14 | ME-01 | improved | 51 |