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Patient P-02123

Synthetic patientMETA-24 · Day 166 · 35–44 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
76%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S03
  2. Day 37 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 37.

Primary contributors, last 14 days
  • Treatment adherence-11
  • GI instability+10
  • Inflammatory activity+10
  • Toxicity-3

What helped?

No interventions yet.

    LIFE OS recommendation
    GI Support Protocol GI-04
    65%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 89% showed improvement
    • median effect visible after 8 days

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    7 min
    improving · +0.3 vs previous 14 d
    Sleep duration
    Wearable
    6.2 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    2.6/10
    improving · +0.5 vs previous 14 d
    Steps
    Wearable
    462
    improving · +232 vs previous 14 d
    GI burden
    Companion
    73.4/100
    improving · -5.9 vs previous 14 d
    Adherence
    Companion
    62.6 %
    worsening · -10.1 vs previous 14 d
    Sleep quality
    Wearable
    38.2/100
    improving · +1.6 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    156 mg/dL
    stable · -2.9 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 39 from the failing basin, 73 from restoration.

    Would help
    • GI-04 GI Support Protocol
      77% improved among 64 similar · onset 8 d · confidence 60%
    • ME-01 Monitoring Escalation
      100% improved among 42 similar · onset 3 d · confidence 68%
    • NP-02 Dietary Support Protocol
      59% improved among 32 similar · onset 10 d · confidence 68%
    • More protein
      GI -5.6 next day on high-intake days · n 18
    Would not help
    • Keep ultra-processed low
      GI +6.1 next day on high-intake days · n 27
    • Keep fat low
      GI +4.7 next day on high-intake days · n 21
    • Keep alcohol low
      GI +4.7 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Ultra-processed food
      +6.1detractor · 95%
    • Protein
      -5.6supporter · 95%
    • Dietary fat load
      +4.7detractor · 95%
    • Alcohol
      +4.7detractor · 95%
    • Simple carbohydrates
      +4detractor · 95%
    • Histamine load
      +3.9detractor · 95%
    • Insoluble fibre
      +2no signal · 42%
    • Caffeine
      -0.5no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery 65
      • WearableResting HR 76 bpm
      • Wearable462 steps/day
      • WearableShort sleep window
    • Butyrate / short-chain fatty acid production 55
      • MicrobiomeButyrate capacity 30/100
      • Daily logFibre intake low in recent food logs
    • Mucosal barrier integrity 50
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • Daily logGI symptom score 73 and rising
    • Inflammatory signalling 50
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • BloodInflammatory load index 66
    • Drug metabolism and exposure 20
      • BloodToxicity index 48
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 2.4 · butyrate capacity 30/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    51 ms
    Sleep
    6.5 h
    Steps
    803
    Resting HR
    74 bpm
    Daily log: GI score 73, nutritional resilience 36, adherence 63.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
    • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Track each bowel movement today: time, stool form, urgency, overnight waking
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • Electrolyte solution, one sachet after any loose stool
    • Fictional demo item: oral nutrition supplement with lunch

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0217019%S0480
    P-0246619%S2079
    P-0204820%S0277
    P-0211523%S14GI-04improved75
    P-0238820%S1175
    P-0257525%S14ME-01improved73
    P-0240319%S0371
    P-0233519%S0470
    P-0255020%S0170
    P-0219219%S0569
    P-0265927%S0969
    P-0235619%S0869