Patient P-02128

Synthetic patientMETA-24 · Day 177 · 55–64 · F · baseline S07Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

19%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S07
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

Toxicity-7
Treatment adherence+6
Inflammatory activity-3
Nutritional resilience+3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

72 min

worsening · -3.0 vs previous 14 d

Sleep duration

Wearable

5.6 h

worsening · -0.5 vs previous 14 d

Energy level

Daily log

5.5/10

worsening · -0.6 vs previous 14 d

Steps

Wearable

7,892

stable · -85 vs previous 14 d

GI burden

Companion

30.2/100

worsening · +9.4 vs previous 14 d

Adherence

Companion

95.4 %

stable · -1.0 vs previous 14 d

Sleep quality

Wearable

25.6/100

worsening · -8.4 vs previous 14 d

Glucose, CGM daily mean

CGM

142 mg/dL

stable · +3.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 60 from the failing basin, 28 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.2 next day on high-intake days · n 22

Would not help

Keep ultra-processed low
GI +3.6 next day on high-intake days · n 19

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.2supporter · 95%
Ultra-processed food
+3.6detractor · 95%
Dietary fat load
+2no signal · 34%
Histamine load
+1.7no signal · 37%
Simple carbohydrates
+0.7no signal · 15%
Alcohol
-0.7no signal · 15%
Insoluble fibre
-0.5no signal · 15%
Caffeine
+0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓25
- DNAIL6 -174 variant raises baseline inflammatory tone
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↓20
- WearableShort sleep window
Mucosal barrier integrity ↓10
- WearableSleep 5.6 h, below personal baseline

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 4.4 · butyrate capacity 75/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 52 ms
Sleep: 5.8 h
Steps: 7,337
Resting HR: 66 bpm

Daily log: GI score 30, nutritional resilience 62, adherence 95.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02483	45%	S06	BR-03	no change	64
P-02280	40%	S07	BR-03	no change	50
P-02087	36%	S01	BR-03	no change	40
P-02267	36%	S09	BR-03	no change	45
P-02638	33%	S01	BR-03	improved	41
P-02354	38%	S01	CR-01	improved	78
P-02491	51%	S09	DT-01	no change	65
P-02462	47%	S12	DT-01	improved	65
P-02235	42%	S14	DT-01	improved	50
P-02274	40%	S15	DT-01	improved	50
P-02339	40%	S03	DT-01	improved	50
P-02518	40%	S17	DT-01	improved	68