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Patient P-02130

Synthetic patientMETA-24 · Day 173 · 55–64 · F · baseline S20Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
29%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S20
  2. Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 GI-04 recommended — GI Support Protocol GI-04
  4. Day 23 Patient declined — Not now

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • GI instability+13
  • Inflammatory activity+13
  • Toxicity+13
  • Nutritional resilience-11
  • Treatment adherence+4

What helped?

  • GI Support Protocol GI-04Day 22
    Declined by patient
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
42 min
worsening · -10.7 vs previous 14 d
Sleep duration
Wearable
6.8 h
stable · -0.0 vs previous 14 d
Energy level
Daily log
5.4/10
worsening · -1.0 vs previous 14 d
Steps
Wearable
4,286
worsening · -688 vs previous 14 d
GI burden
Companion
24.4/100
worsening · +7.0 vs previous 14 d
Adherence
Companion
96.6 %
stable · +2.6 vs previous 14 d
Sleep quality
Wearable
48.1/100
worsening · -3.7 vs previous 14 d
Glucose, CGM daily mean
CGM
135 mg/dL
stable · +4.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 66 from the failing basin, 30 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -5.7 next day on high-intake days · n 22
Would not help
  • Keep fat low
    GI +4 next day on high-intake days · n 16
  • Keep caffeine low
    GI +3.8 next day on high-intake days · n 21
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -5.7supporter · 95%
  • Dietary fat load
    +4detractor · 95%
  • Caffeine
    +3.8detractor · 95%
  • Ultra-processed food
    -1.3no signal · 30%
  • Alcohol
    +1.2no signal · 32%
  • Insoluble fibre
    -1no signal · 24%
  • Histamine load
    -0.9no signal · 23%
  • Simple carbohydrates
    +0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 30/100
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Inflammatory signalling ↑20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
Microbiome
Shannon diversity 3 · butyrate capacity 30/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
52 ms
Sleep
6.9 h
Steps
3,846
Resting HR
70 bpm
Daily log: GI score 24, nutritional resilience 58, adherence 97.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0230352%S15GI-04improved48
P-0261649%S06——51
P-0264549%S02HY-01improved56
P-0204548%S07——52
P-0223548%S14DT-01improved50
P-0231248%S20——54
P-0239448%S12——62
P-0257348%S10——52
P-0260248%S20HY-01improved52
P-0269748%S07GI-04improved56
P-0216947%S17——43
P-0203346%S06GI-04improved51