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Patient P-02148

Synthetic patientMETA-24 · Day 104 · 45–54 · F · baseline S04Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S04
  2. Day 24 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 24.

Primary contributors, last 14 days
  • Toxicity-17
  • GI instability-16
  • Nutritional resilience+11
  • Inflammatory activity-9
  • Treatment adherence+6

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    45 min
    improving · +5.1 vs previous 14 d
    Sleep duration
    Wearable
    5.8 h
    stable · +0.0 vs previous 14 d
    Energy level
    Daily log
    5.9/10
    stable · +0.2 vs previous 14 d
    Steps
    Wearable
    5,645
    stable · +215 vs previous 14 d
    GI burden
    Companion
    18.5/100
    improving · -4.6 vs previous 14 d
    Adherence
    Companion
    96.8 %
    stable · +1.1 vs previous 14 d
    Sleep quality
    Wearable
    36.7/100
    worsening · -1.9 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    142 mg/dL
    stable · +0.1 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 77 from the failing basin, 15 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein (supports)
      perturbation · steering +4.9
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -2.9 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • Caffeine
      perturbation · steering -5.5
    • Poor-sleep week
      perturbation · steering -3
    • Caffeine
      detractor · GI +2.9 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Caffeine
      +2.9detractor · 95%
    • Protein
      -2.9supporter · 95%
    • Histamine load
      -1.1no signal · 31%
    • Insoluble fibre
      +0.9no signal · 31%
    • Ultra-processed food
      -0.9no signal · 26%
    • Dietary fat load
      -0.8no signal · 15%
    • Simple carbohydrates
      -0.6no signal · 15%
    • Alcohol
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery ↑45
      • WearableResting HR 72 bpm
      • WearableShort sleep window
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Mucosal barrier integrity ↓10
      • WearableSleep 5.8 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 4.6 · butyrate capacity 57/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    5.9 h
    Steps
    5,970
    Resting HR
    76 bpm
    Daily log: GI score 19, nutritional resilience 68, adherence 97.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

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    P-0245538%S09DT-01improved50