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Patient P-02177

Synthetic patientMETA-24 · Day 180 · 25–34 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
8%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S03
  2. Day 127 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 127.

Primary contributors, last 14 days
  • GI instability-16
  • Inflammatory activity-15
  • Nutritional resilience+11
  • Toxicity-9
  • Treatment adherence+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    71 min
    improving · +3.0 vs previous 14 d
    Sleep duration
    Wearable
    7.9 h
    stable · +0.3 vs previous 14 d
    Energy level
    Daily log
    7.2/10
    improving · +0.8 vs previous 14 d
    Steps
    Wearable
    8,245
    improving · +708 vs previous 14 d
    GI burden
    Companion
    9.8/100
    improving · -8.4 vs previous 14 d
    Adherence
    Companion
    91 %
    worsening · -4.3 vs previous 14 d
    Sleep quality
    Wearable
    67.1/100
    improving · +5.8 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    120 mg/dL
    improving · -6.1 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 86 from the failing basin, 17 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -6 next day on high-intake days · n 23
    Would not help
    • Keep alcohol low
      GI +5.9 next day on high-intake days · n 17
    • Keep histamine low
      GI +4.9 next day on high-intake days · n 17
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -6supporter · 95%
    • Alcohol
      +5.9detractor · 95%
    • Histamine load
      +4.9detractor · 95%
    • Caffeine
      +1.4no signal · 30%
    • Insoluble fibre
      +1no signal · 20%
    • Simple carbohydrates
      +0.4no signal · 15%
    • Dietary fat load
      +0.2no signal · 15%
    • Ultra-processed food
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.5 · butyrate capacity 53/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    49 ms
    Sleep
    8.0 h
    Steps
    7,423
    Resting HR
    57 bpm
    Daily log: GI score 10, nutritional resilience 66, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0203131%S12AD-05improved47
    P-0228531%S14AD-05no change39
    P-0248341%S06BR-03no change64
    P-0226734%S09BR-03no change45
    P-0228034%S07BR-03no change50
    P-0235433%S01CR-01improved78
    P-0249143%S09DT-01no change65
    P-0246242%S12DT-01improved65
    P-0251842%S17DT-01improved68
    P-0233937%S03DT-01improved50
    P-0223536%S14DT-01improved50
    P-0245536%S09DT-01improved50