Patient P-02303

Synthetic patientMETA-24 · Day 179 · 55–64 · F · baseline S15Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S15
Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 GI-04 recommended — GI Support Protocol GI-04
Day 23 Patient accepted — Started GI-04 in the companion
Day 31 GI symptom burden −21% vs expected — GI Support Protocol GI-04
Day 37 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 13.

Primary contributors, last 14 days

GI instability+5
Inflammatory activity+3
Toxicity+2

What helped?

GI Support Protocol GI-04Day 22
Result: symptom burden −21%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

59 min

stable · -0.9 vs previous 14 d

Sleep duration

Wearable

7.8 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

5.6/10

worsening · -0.6 vs previous 14 d

Steps

Wearable

7,216

stable · -130 vs previous 14 d

GI burden

Companion

18.8/100

worsening · +4.7 vs previous 14 d

Adherence

Companion

96.3 %

stable · +3.3 vs previous 14 d

Sleep quality

Wearable

61.8/100

worsening · -3.6 vs previous 14 d

Glucose, CGM daily mean

CGM

123 mg/dL

stable · +2.2 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 73 from the failing basin, 30 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -3.7 next day on high-intake days · n 25

Would not help

Keep ultra-processed low
GI +3.8 next day on high-intake days · n 15
Keep alcohol low
GI +3.3 next day on high-intake days · n 21
Keep simple carbs low
GI +3 next day on high-intake days · n 23

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Ultra-processed food
+3.8detractor · 95%
Protein
-3.7supporter · 95%
Alcohol
+3.3detractor · 95%
Simple carbohydrates
+3detractor · 95%
Caffeine
+2.3detractor · 70%
Dietary fat load
+2.2detractor · 83%
Histamine load
+0.9no signal · 26%
Insoluble fibre
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 32/100
- MicrobiomeF. prausnitzii depleted
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Intermediate metabolizer
Expected exposure

Microbiome

Shannon diversity 2.3 · butyrate capacity 32/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 54 ms
Sleep: 8.0 h
Steps: 7,482
Resting HR: 62 bpm

Daily log: GI score 19, nutritional resilience 67, adherence 96.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02494	55%	S09	GI-04	improved	47
P-02169	54%	S17	—	—	43
P-02235	53%	S14	DT-01	improved	50
P-02573	53%	S10	—	—	52
P-02665	53%	S15	—	—	56
P-02130	52%	S20	—	—	49
P-02070	51%	S11	—	—	55
P-02105	51%	S08	—	—	54
P-02295	51%	S04	—	—	50
P-02645	51%	S02	HY-01	improved	56
P-02685	51%	S16	DT-01	improved	47
P-02147	50%	S13	GI-04	improved	58