Patient P-02398
Synthetic patientMETA-24 · Day 175 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
43%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S06
- Day 115 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 122 GI-04 recommended — GI Support Protocol GI-04
- Day 123 Patient accepted — Started GI-04 in the companion
- Day 131 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 137 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 115.
Primary contributors, last 14 days
- Toxicity-12
- Inflammatory activity-10
- Nutritional resilience+6
- GI instability-5
- Treatment adherence-4
What helped?
- GI Support Protocol GI-04Day 122Result: symptom burden −23%
LIFE OS recommendation
Dietary Support Protocol NP-02
47%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 69% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable21 min
improving · +3.2 vs previous 14 d
Sleep duration
Wearable4.9 h
stable · +0.0 vs previous 14 d
Energy level
Daily log4/10
improving · +0.4 vs previous 14 d
Steps
Wearable2,206
improving · +140 vs previous 14 d
GI burden
Companion45.9/100
improving · -5.9 vs previous 14 d
Adherence
Companion71 %
stable · -1.4 vs previous 14 d
Sleep quality
Wearable24.6/100
stable · +0.6 vs previous 14 d
Glucose, CGM daily mean
CGM146 mg/dL
stable · -2.2 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 49 from the failing basin, 41 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +36
- Protein (supports)perturbation · steering +13
- Daily walks resumedperturbation · steering +3.3
- Proteinsupporter · GI -7 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Ultra-processed foodperturbation · steering -12.1
- Dietary fat loadperturbation · steering -11.6
- FUT2 non-secretorhidden · steering -10.6
- Ultra-processed fooddetractor · GI +7.2 next day
- Dietary fat loaddetractor · GI +6.9 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Ultra-processed food+7.2detractor · 95%
- Protein-7supporter · 95%
- Dietary fat load+6.9detractor · 95%
- Histamine load+5.5detractor · 95%
- Simple carbohydrates+5.3detractor · 95%
- Alcohol-2.4no signal · 48%
- Caffeine+1no signal · 18%
- Insoluble fibre+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 46 and rising
- WearableSleep 4.9 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 25/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑40
- Wearable2,206 steps/day
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 25/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 48 ms
- Sleep
- 5.2 h
- Steps
- 1,078
- Resting HR
- 70 bpm
Daily log: GI score 46, nutritional resilience 50, adherence 71.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.