Patient P-02406
Therapy response
Declining
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
15%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S11
- Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 15.
Primary contributors, last 14 days
- Treatment adherence+9
- GI instability+6
- Nutritional resilience+5
- Toxicity-5
- Inflammatory activity+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable28 min
stable · +1.2 vs previous 14 d
Sleep duration
Wearable6.9 h
stable · +0.1 vs previous 14 d
Energy level
Daily log6.7/10
improving · +0.3 vs previous 14 d
Steps
Wearable3,307
stable · +5 vs previous 14 d
GI burden
Companion15.9/100
improving · -5.5 vs previous 14 d
Adherence
Companion98.6 %
stable · -1.8 vs previous 14 d
Sleep quality
Wearable60.9/100
improving · +3.8 vs previous 14 d
Glucose, CGM daily mean
CGM125 mg/dL
stable · -2.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 78 from the failing basin, 16 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -5.1 next day on high-intake days · n 17
Would not help
- Keep ultra-processed lowGI +3.9 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.1supporter · 95%
- Ultra-processed food+3.9detractor · 95%
- Histamine load-1.5no signal · 29%
- Caffeine+1.5no signal · 37%
- Dietary fat load+0.8no signal · 21%
- Alcohol+0.6no signal · 15%
- Simple carbohydrates+0.1no signal · 15%
- Insoluble fibre0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓45
- WearableResting HR 73 bpm
- Wearable3,307 steps/day
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 66 ms
- Sleep
- 7.1 h
- Steps
- 4,144
- Resting HR
- 73 bpm
Daily log: GI score 16, nutritional resilience 68, adherence 99.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02147 | 54% | S13 | GI-04 | improved | 58 |
| P-02218 | 48% | S01 | DT-01 | improved | 61 |
| P-02167 | 46% | S02 | HY-01 | improved | 54 |
| P-02645 | 46% | S02 | HY-01 | improved | 56 |
| P-02697 | 46% | S07 | GI-04 | improved | 56 |
| P-02235 | 45% | S14 | DT-01 | improved | 50 |
| P-02303 | 45% | S15 | GI-04 | improved | 48 |
| P-02586 | 45% | S18 | DT-01 | improved | 56 |
| P-02602 | 45% | S20 | HY-01 | improved | 52 |
| P-02479 | 44% | S13 | DT-01 | improved | 48 |
| P-02538 | 44% | S02 | GI-04 | improved | 59 |
| P-02494 | 43% | S09 | GI-04 | improved | 47 |