700 patients110,866 observations180 daysLIVE

Patient P-02410

Synthetic patientMETA-24 · Day 170 · 35–44 · M · baseline S01Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Stable
Inflammatory state
Deteriorating
Nutritional resilience
Stable
Discontinuation risk
58%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S01
  2. Day 72 Trajectory diverged from predictionObserved response fell below the model's expected path.
  3. Day 75 GI-04 recommendedGI Support Protocol GI-04
  4. Day 76 Patient acceptedStarted GI-04 in the companion
  5. Day 84 GI symptom burden −32% vs expectedGI Support Protocol GI-04
  6. Day 90 Tolerance state changedUnstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 72.

Primary contributors, last 14 days
  • Inflammatory activity+8
  • GI instability+4
  • Treatment adherence+3
  • Toxicity+3
  • Nutritional resilience-2

What helped?

  • GI Support Protocol GI-04Day 75
    Result: symptom burden −32%
LIFE OS recommendation
Monitoring Escalation ME-01
73%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 100% showed improvement
  • median effect visible after 3 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
29 min
improving · +9.4 vs previous 14 d
Sleep duration
Wearable
6 h
stable · +0.2 vs previous 14 d
Energy level
Daily log
3.7/10
improving · +0.6 vs previous 14 d
Steps
Wearable
3,445
improving · +930 vs previous 14 d
GI burden
Companion
53.1/100
improving · -4.2 vs previous 14 d
Adherence
Companion
49.7 %
worsening · -2.9 vs previous 14 d
Sleep quality
Wearable
38.1/100
improving · +3.4 vs previous 14 d
Glucose, CGM daily mean
CGM
139 mg/dL
stable · -1.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 39 from the failing basin, 51 from restoration.

Would help
  • ME-01 Monitoring Escalation
    100% improved among 42 similar · onset 3 d · confidence 61%
  • NP-02 Dietary Support Protocol
    59% improved among 32 similar · onset 10 d · confidence 61%
  • CR-01 Clinician Review
    100% improved among 6 similar · onset 5 d · confidence 61%
  • More protein
    GI -5.5 next day on high-intake days · n 22
  • More alcohol
    GI -3.6 next day on high-intake days · n 14
Would not help
  • Keep fat low
    GI +5.2 next day on high-intake days · n 19
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -5.5supporter · 95%
  • Dietary fat load
    +5.2detractor · 95%
  • Alcohol
    -3.6supporter · 79%
  • Insoluble fibre
    +1.6no signal · 36%
  • Ultra-processed food
    -1.4no signal · 32%
  • Caffeine
    -0.5no signal · 15%
  • Histamine load
    -0.4no signal · 15%
  • Simple carbohydrates
    +0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production 55
    • MicrobiomeButyrate capacity 27/100
    • Daily logFibre intake low in recent food logs
  • Inflammatory signalling 45
    • MicrobiomeBacteroides fragilis expansion
    • BloodInflammatory load index 50
  • Autonomic recovery 40
    • Wearable3,445 steps/day
    • WearableShort sleep window
  • Mucosal barrier integrity 30
    • Daily logGI symptom score 53 and rising
    • WearableSleep 6.0 h, below personal baseline
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Normal metabolizer
    Expected exposure
  • GLP1R rs6923761 A
    Altered receptor sensitivity
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 27/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
56 ms
Sleep
6.1 h
Steps
3,686
Resting HR
67 bpm
Daily log: GI score 53, nutritional resilience 44, adherence 50.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0204823%S0277
P-0211523%S14GI-04improved75
P-0238822%S1175
P-0257523%S14ME-01improved73
P-0240322%S0371
P-0233523%S0470
P-0255023%S0170
P-0219222%S0569
P-0265928%S0969
P-0221422%S08SC-12no change69
P-0235623%S0869
P-0229322%S15HY-01no change68