Patient P-02460
Synthetic patientMETA-24 · Day 110 · 55–64 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
50%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S18
- Day 72 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 74 GI-04 recommended — GI Support Protocol GI-04
- Day 75 Patient accepted — Started GI-04 in the companion
- Day 83 GI symptom burden −33% vs expected — GI Support Protocol GI-04
- Day 89 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 72.
Primary contributors, last 14 days
- Treatment adherence-28
- Inflammatory activity-7
- Nutritional resilience+4
- GI instability-3
- Toxicity-3
What helped?
- GI Support Protocol GI-04Day 74Result: symptom burden −33%
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 73% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable54 min
improving · +4.9 vs previous 14 d
Sleep duration
Wearable8 h
stable · +0.0 vs previous 14 d
Energy level
Daily log4.2/10
worsening · -0.6 vs previous 14 d
Steps
Wearable6,269
improving · +437 vs previous 14 d
GI burden
Companion52.3/100
stable · +0.9 vs previous 14 d
Adherence
Companion58.9 %
worsening · -16.8 vs previous 14 d
Sleep quality
Wearable56.1/100
stable · -1.0 vs previous 14 d
Glucose, CGM daily mean
CGM134 mg/dL
stable · -3.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 44 from the failing basin, 46 from restoration.
Would help
Would not help
- Keep histamine lowGI +3.2 next day on high-intake days · n 21
- Keep fat lowGI +2.7 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+3.2detractor · 95%
- Protein-3.2supporter · 95%
- Dietary fat load+2.7detractor · 95%
- Caffeine+1.3no signal · 39%
- Simple carbohydrates+1no signal · 24%
- Insoluble fibre-0.5no signal · 15%
- Ultra-processed food-0.3no signal · 15%
- Alcohol-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 52 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 28/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 47
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3.1 · butyrate capacity 28/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 56 ms
- Sleep
- 7.2 h
- Steps
- 5,828
- Resting HR
- 65 bpm
Daily log: GI score 52, nutritional resilience 47, adherence 59.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02060 | 47% | S14 | GI-04 | improved | 54 |
| P-02299 | 43% | S14 | GI-04 | improved | 59 |
| P-02674 | 37% | S02 | NP-02 | improved | 48 |
| P-02165 | 34% | S14 | ME-01 | improved | 59 |
| P-02176 | 33% | S14 | GI-04 | improved | 52 |
| P-02398 | 33% | S06 | GI-04 | improved | 63 |
| P-02508 | 33% | S14 | ME-01 | improved | 51 |
| P-02216 | 32% | S11 | GI-04 | improved | 53 |
| P-02298 | 32% | S14 | GI-04 | improved | 65 |
| P-02410 | 32% | S01 | GI-04 | improved | 55 |
| P-02575 | 32% | S14 | ME-01 | improved | 73 |
| P-02666 | 32% | S14 | ME-01 | improved | 51 |