Patient P-02522

Synthetic patientMETA-24 · Day 166 · 75+ · F · baseline S01Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Declining

Discontinuation risk

18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S01
Day 108 BR-03 recommended — Behavioural Recommendation BR-03
Day 109 Patient accepted — Started BR-03 in the companion
Day 116 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 116 No meaningful change — Behavioural Recommendation BR-03

What changed?

Trajectory began diverging from predicted response on Day 116.

Primary contributors, last 14 days

Nutritional resilience-8
Treatment adherence+3
GI instability+2

What helped?

Behavioural Recommendation BR-03Day 108
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

67 min

stable · -2.6 vs previous 14 d

Sleep duration

Wearable

5.9 h

stable · -0.0 vs previous 14 d

Energy level

Daily log

5.9/10

stable · +0.2 vs previous 14 d

Steps

Wearable

8,082

stable · -245 vs previous 14 d

GI burden

Companion

18.5/100

improving · -0.9 vs previous 14 d

Adherence

Companion

83.5 %

stable · -3.3 vs previous 14 d

Sleep quality

Wearable

42.6/100

stable · -0.2 vs previous 14 d

Glucose, CGM daily mean

CGM

130 mg/dL

stable · +1.2 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 70 from the failing basin, 38 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Behavioural Recommendation BR-03
intervention · steering +5
Protein (supports)
perturbation · steering +4.9
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -2.8 next day

Main detractors to watch

FUT2 non-secretor
hidden · steering -10.6
IL6 high-expression variant
hidden · steering -7.3
Histamine load
perturbation · steering -6.7
Alcohol
perturbation · steering -6
Histamine load
detractor · GI +3.9 next day
Alcohol
detractor · GI +3.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+3.9detractor · 95%
Alcohol
+3.3detractor · 95%
Protein
-2.8supporter · 85%
Simple carbohydrates
-1.4no signal · 37%
Insoluble fibre
+1.1no signal · 27%
Caffeine
+1.1no signal · 30%
Ultra-processed food
+0.9no signal · 31%
Dietary fat load
+0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓70
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.9 h, below personal baseline
Inflammatory signalling ↓25
- DNAIL6 -174 variant raises baseline inflammatory tone
Autonomic recovery ↓20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 3.9 · butyrate capacity 78/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 57 ms
Sleep: 6.2 h
Steps: 7,469
Resting HR: 57 bpm

Daily log: GI score 19, nutritional resilience 66, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02031	46%	S12	AD-05	improved	47
P-02016	40%	S20	DT-01	improved	27
P-02484	39%	S15	GI-04	improved	49
P-02479	38%	S13	DT-01	improved	48
P-02494	38%	S09	GI-04	improved	47
P-02303	37%	S15	GI-04	improved	48
P-02331	37%	S14	BR-03	improved	34
P-02339	37%	S03	DT-01	improved	50
P-02685	37%	S16	DT-01	improved	47
P-02697	37%	S07	GI-04	improved	56
P-02033	36%	S06	GI-04	improved	51
P-02391	36%	S19	HY-01	improved	53