Patient P-02525

Synthetic patientMETA-24 · Day 170 · 55–64 · F · baseline S04Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

50%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S04
Day 123 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 123.

Primary contributors, last 14 days

GI instability+23
Inflammatory activity+18
Nutritional resilience-17
Toxicity+8
Treatment adherence+5

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

74 min

worsening · -3.7 vs previous 14 d

Sleep duration

Wearable

7 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

4.8/10

stable · +0.0 vs previous 14 d

Steps

Wearable

7,195

worsening · -661 vs previous 14 d

GI burden

Companion

30.3/100

worsening · +1.5 vs previous 14 d

Adherence

Companion

86.4 %

stable · -2.0 vs previous 14 d

Sleep quality

Wearable

55.1/100

stable · -1.5 vs previous 14 d

Glucose, CGM daily mean

CGM

140 mg/dL

stable · +1.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 51 from the failing basin, 49 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.8 next day on high-intake days · n 21

Would not help

BR-03 Behavioural Recommendation
only 27% improved among 11 similar
Keep alcohol low
GI +3.6 next day on high-intake days · n 17
Keep histamine low
GI +3.3 next day on high-intake days · n 23

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.8supporter · 95%
Alcohol
+3.6detractor · 95%
Histamine load
+3.3detractor · 95%
Insoluble fibre
-1.6no signal · 48%
Caffeine
+0.5no signal · 15%
Ultra-processed food
+0.5no signal · 15%
Simple carbohydrates
+0.2no signal · 15%
Dietary fat load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
Autonomic recovery ↓25
- WearableResting HR 74 bpm
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3 · butyrate capacity 50/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 66 ms
Sleep: 7.7 h
Steps: 7,830
Resting HR: 70 bpm

Daily log: GI score 30, nutritional resilience 53, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02016	37%	S20	DT-01	improved	27
P-02484	37%	S15	GI-04	improved	49
P-02685	36%	S16	DT-01	improved	47
P-02479	35%	S13	DT-01	improved	48
P-02223	34%	S20	HY-01	improved	49
P-02339	34%	S03	DT-01	improved	50
P-02031	33%	S12	AD-05	improved	47
P-02274	33%	S15	DT-01	improved	50
P-02303	33%	S15	GI-04	improved	48
P-02395	33%	S12	DT-01	improved	57
P-02494	33%	S09	GI-04	improved	47
P-02638	33%	S01	BR-03	improved	41