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Patient P-02628

Synthetic patientMETA-24 · Day 174 · 45–54 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S14
  2. Day 69 Trajectory diverged from predictionObserved response fell below the model's expected path.
  3. Day 71 SC-12 recommendedSupportive Compound SC-12
  4. Day 72 Patient acceptedStarted SC-12 in the companion
  5. Day 78 GI symptom burden −18% vs expectedSupportive Compound SC-12
  6. Day 84 Tolerance state changedUnstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 69.

Primary contributors, last 14 days
  • GI instability+6
  • Inflammatory activity+2

What helped?

  • Supportive Compound SC-12Day 71
    Result: symptom burden −18%
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 89% showed improvement
  • median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
5 min
stable · +0.3 vs previous 14 d
Sleep duration
Wearable
5.6 h
improving · +0.3 vs previous 14 d
Energy level
Daily log
2.4/10
improving · +0.3 vs previous 14 d
Steps
Wearable
955
worsening · -32 vs previous 14 d
GI burden
Companion
63.3/100
stable · -2.5 vs previous 14 d
Adherence
Companion
50.6 %
stable · +0.3 vs previous 14 d
Sleep quality
Wearable
15.5/100
improving · +2.9 vs previous 14 d
Glucose, CGM daily mean
CGM
155 mg/dL
stable · -0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 26 from the failing basin, 66 from restoration.

Would help
  • GI-04 GI Support Protocol
    77% improved among 65 similar · onset 8 d · confidence 93%
  • ME-01 Monitoring Escalation
    100% improved among 42 similar · onset 3 d · confidence 70%
  • NP-02 Dietary Support Protocol
    59% improved among 32 similar · onset 10 d · confidence 70%
  • More protein
    GI -4.4 next day on high-intake days · n 21
Would not help
  • Keep fat low
    GI +3.6 next day on high-intake days · n 23
  • Keep ultra-processed low
    GI +3.5 next day on high-intake days · n 18
  • Keep simple carbs low
    GI +3 next day on high-intake days · n 18
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -4.4supporter · 95%
  • Dietary fat load
    +3.6detractor · 95%
  • Ultra-processed food
    +3.5detractor · 95%
  • Simple carbohydrates
    +3detractor · 89%
  • Alcohol
    -1.5no signal · 40%
  • Histamine load
    -1.2no signal · 37%
  • Caffeine
    -0.4no signal · 15%
  • Insoluble fibre
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Inflammatory signalling 65
    • DNAIL6 -174 variant raises baseline inflammatory tone
    • BloodInflammatory load index 58
    • WearableHRV 35 ms, trending down
  • Autonomic recovery 65
    • WearableResting HR 73 bpm
    • Wearable955 steps/day
    • WearableShort sleep window
  • Mucosal barrier integrity 60
    • MicrobiomeAkkermansia low → thinner mucus layer
    • Daily logGI symptom score 63 and rising
    • WearableSleep 5.6 h, below personal baseline
  • Butyrate / short-chain fatty acid production 55
    • MicrobiomeButyrate capacity 39/100
    • Daily logFibre intake low in recent food logs
  • Drug metabolism and exposure 20
    • BloodToxicity index 44
DNA
Fictional pharmacogenomic panel
  • IL6 -174 G/C
    Higher inflammatory tone
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 2.2 · butyrate capacity 39/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
5.8 h
Steps
680
Resting HR
74 bpm
Daily log: GI score 63, nutritional resilience 41, adherence 51.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0234856%S14GI-04improved49
P-0253556%S14SC-12improved50
P-0232055%S14NP-02improved50
P-0251655%S14SC-12improved51
P-0257455%S14ME-01improved45
P-0265754%S1442
P-0201452%S14GI-04improved48
P-0231651%S14GI-04improved51
P-0205750%S14GI-04improved47
P-0225350%S14NP-02no change41
P-0267050%S14SC-12improved45
P-0205949%S03SC-12improved41