700 patients110,866 observations180 daysLIVE

Patient P-02689

Synthetic patientMETA-24 · Day 174 · 55–64 · F · baseline S13Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
39%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S13
  2. Day 22 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 22.

Primary contributors, last 14 days
  • GI instability+17
  • Inflammatory activity+12
  • Treatment adherence+9
  • Nutritional resilience-8

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    47 min
    worsening · -3.3 vs previous 14 d
    Sleep duration
    Wearable
    8.1 h
    stable · +0.0 vs previous 14 d
    Energy level
    Daily log
    6.3/10
    stable · +0.0 vs previous 14 d
    Steps
    Wearable
    5,311
    worsening · -598 vs previous 14 d
    GI burden
    Companion
    28.7/100
    stable · -0.6 vs previous 14 d
    Adherence
    Companion
    97.2 %
    stable · +3.0 vs previous 14 d
    Sleep quality
    Wearable
    65.1/100
    stable · -1.2 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    132 mg/dL
    stable · -0.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 86 from the failing basin, 19 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -5.9 next day on high-intake days · n 22
    Would not help
    • Keep caffeine low
      GI +5.8 next day on high-intake days · n 25
    • Keep histamine low
      GI +5.5 next day on high-intake days · n 23
    • Keep ultra-processed low
      GI +4.5 next day on high-intake days · n 24
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.9supporter · 95%
    • Caffeine
      +5.8detractor · 95%
    • Histamine load
      +5.5detractor · 95%
    • Ultra-processed food
      +4.5detractor · 95%
    • Alcohol
      +2.7detractor · 59%
    • Insoluble fibre
      -1.7no signal · 37%
    • Dietary fat load
      -1.3no signal · 23%
    • Simple carbohydrates
      -1.2no signal · 24%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Inflammatory signalling 25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.3 · butyrate capacity 75/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    55 ms
    Sleep
    7.7 h
    Steps
    6,494
    Resting HR
    68 bpm
    Daily log: GI score 29, nutritional resilience 59, adherence 97.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0245039%S12NP-02improved92
    P-0206836%S14NP-02improved83
    P-0241536%S17GI-04improved86
    P-0266735%S08HY-01improved77
    P-0219334%S11CR-01improved87
    P-0227734%S05AD-05improved92
    P-0248634%S10ME-01improved86
    P-0211533%S14GI-04improved75
    P-0212733%S11SC-12improved73
    P-0229833%S14GI-04improved65
    P-0263033%S17NP-02improved76
    P-0235432%S01CR-01improved78