Patient P-03052
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S03
- Day 134 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 134.
Primary contributors, last 14 days
- GI instability+24
- Nutritional resilience-12
- Inflammatory activity+9
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
60%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑40
- BloodInflammatory load index 41
- WearableHRV 31 ms, trending down
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 46 and rising
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 4.3 · butyrate capacity 57/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 31 ms
- Sleep
- 7.3 h
- Steps
- 8,584
- Resting HR
- 69 bpm
Daily log: GI score 46, nutritional resilience 52, adherence 90.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03204 | 36% | S16 | AD-05 | improved | 48 |
| P-03105 | 34% | S12 | AD-05 | no change | 60 |
| P-03424 | 33% | S12 | AD-05 | improved | 41 |
| P-03482 | 32% | S05 | AD-05 | no change | 67 |
| P-03111 | 31% | S07 | AD-05 | no change | 48 |
| P-03369 | 30% | S18 | AD-05 | no change | 37 |
| P-03380 | 30% | S16 | AD-05 | improved | 34 |
| P-03034 | 29% | S14 | AD-05 | no change | 30 |
| P-03351 | 29% | S07 | AD-05 | no change | 51 |
| P-03129 | 28% | S18 | AD-05 | no change | 32 |
| P-03158 | 28% | S17 | AD-05 | no change | 37 |
| P-03122 | 26% | S13 | AD-05 | no change | 40 |