Patient P-03052
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S03
- Day 134 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 134.
Primary contributors, last 14 days
- GI instability+24
- Nutritional resilience-12
- Inflammatory activity+9
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
60%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.2/10
worsening · -1.0 vs previous 14 d
Stress level
Daily log6.3/10
worsening · +1.0 vs previous 14 d
Pessimism score
Daily log6/10
worsening · +1.0 vs previous 14 d
Sleep quality
Wearable44.6/100
worsening · -10.4 vs previous 14 d
Libido
Daily log4/10
worsening · -0.7 vs previous 14 d
HRV
Wearable30.7 ms
worsening · -4.6 vs previous 14 d
Toxicity
Blood22/100
worsening · +2.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 41 from the failing basin, 48 from restoration.
Would help
- GI-04 GI Support Protocol84% improved among 25 similar · onset 8 d · confidence 58%
- DT-01 Dosing / Timing Recommendation85% improved among 13 similar · onset 5 d · confidence 70%
- ME-01 Monitoring Escalation100% improved among 6 similar · onset 3 d · confidence 70%
- More proteinGI -6.2 next day on high-intake days · n 20
Would not help
- AD-05 Adherence Supportonly 25% improved among 12 similar
- Keep caffeine lowGI +5.1 next day on high-intake days · n 17
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.2supporter · 95%
- Caffeine+5.1detractor · 95%
- Histamine load-1.7no signal · 31%
- Alcohol-1.6no signal · 35%
- Dietary fat load+1.3no signal · 24%
- Lactose-0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑40
- BloodInflammatory load index 41
- WearableHRV 31 ms, trending down
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 46 and rising
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 4.3 · butyrate capacity 57/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 31 ms
- Sleep
- 7.3 h
- Steps
- 8,584
- Resting HR
- 69 bpm
Daily log: GI score 46, nutritional resilience 52, adherence 90.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03484 | 41% | S07 | DT-01 | improved | 49 |
| P-03178 | 38% | S11 | GI-04 | improved | 54 |
| P-03255 | 37% | S01 | HY-01 | improved | 53 |
| P-03374 | 37% | S19 | ME-01 | improved | 55 |
| P-03144 | 36% | S16 | HY-01 | improved | 52 |
| P-03179 | 36% | S05 | GI-04 | improved | 52 |
| P-03204 | 36% | S16 | AD-05 | improved | 48 |
| P-03379 | 35% | S12 | GI-04 | improved | 51 |
| P-03277 | 34% | S14 | BR-03 | improved | 41 |
| P-03031 | 33% | S16 | CR-01 | improved | 49 |
| P-03057 | 33% | S14 | NP-02 | improved | 64 |
| P-03252 | 33% | S13 | SC-12 | improved | 68 |