Patient P-03111
Therapy response
Stable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
16%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S07
- Day 90 AD-05 recommended — Adherence Support AD-05
- Day 91 Patient accepted — Started AD-05 in the companion
- Day 96 No meaningful change — Adherence Support AD-05
- Day 107 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 107.
Primary contributors, last 14 days
- GI instability-12
- Toxicity+12
- Inflammatory activity+10
- Nutritional resilience+4
- Treatment adherence+2
What helped?
- Adherence Support AD-05Day 90Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log5.8/10
stable · +0.0 vs previous 14 d
Stress level
Daily log4/10
stable · +0.1 vs previous 14 d
Pessimism score
Daily log3.6/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable41.9/100
improving · +4.5 vs previous 14 d
Libido
Daily log4.8/10
worsening · -0.3 vs previous 14 d
HRV
Wearable37.3 ms
stable · -1.1 vs previous 14 d
Toxicity
Blood29.1/100
worsening · +7.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 73 from the failing basin, 31 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -3.7 next day on high-intake days · n 20
Would not help
- AD-05 Adherence Supportalready tried, no meaningful change
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.7supporter · 95%
- Dietary fat load+0.9no signal · 28%
- Lactose+0.7no signal · 21%
- Caffeine-0.5no signal · 16%
- Histamine load-0.4no signal · 15%
- Alcohol+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 37 ms, trending down
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 3.3 · butyrate capacity 68/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 38 ms
- Sleep
- 6.9 h
- Steps
- 7,777
- Resting HR
- 62 bpm
Daily log: GI score 12, nutritional resilience 70, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.