Patient P-03151
Therapy response
Stable
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
55%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S18
- Day 96 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 96.
Primary contributors, last 14 days
- GI instability-18
- Treatment adherence-16
- Nutritional resilience+9
- Inflammatory activity-3
- Toxicity+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
62%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log2.3/10
improving · +1.0 vs previous 14 d
Stress level
Daily log6.8/10
improving · -0.8 vs previous 14 d
Pessimism score
Daily log5.6/10
improving · -0.4 vs previous 14 d
Sleep quality
Wearable31.2/100
improving · +11.4 vs previous 14 d
Libido
Daily log2.8/10
improving · +0.6 vs previous 14 d
HRV
Wearable38.7 ms
improving · +5.1 vs previous 14 d
Toxicity
Blood50.8/100
stable · +1.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 33 from the failing basin, 56 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +10.1
- Proteinsupporter · GI -5.7 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Dietary fat loadperturbation · steering -9.1
- Lactoseperturbation · steering -8.2
- Bacteroides fragilis elevatedhidden · steering -7.4
- Dietary fat loaddetractor · GI +4.5 next day
- Lactosedetractor · GI +4.3 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.7supporter · 95%
- Dietary fat load+4.5detractor · 95%
- Lactose+4.3detractor · 95%
- Alcohol-1.7no signal · 36%
- Caffeine-0.9no signal · 17%
- Histamine load-0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 34/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- WearableSleep 5.9 h, below personal baseline
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 51
- Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 55
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.2 · butyrate capacity 34/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 5.3 h
- Steps
- 7,364
- Resting HR
- 71 bpm
Daily log: GI score 53, nutritional resilience 39, adherence 61.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.